GDCB integrates experimental and computational research approaches with instructional and pedagogical innovation in three primary focus areas. The GDCB Department is dedicated to biological discovery and excellence in undergraduate and graduate education, with research and teaching missions encompassing fundamental cellular and subcellular processes, including genome dynamics, cell structure and function, cellular metabolism, cellular response to environmental and developmental signals, and molecular mechanisms of development. The GDCB Department has identified 3 primary focus areas in which it already enjoys a strong representation:

Genome Dynamics: Structure, function and activity of the genome

This includes vital processes required for the maintenance, inheritance and expression of the genetic material; ranging from transcriptional and post-transcriptional regulation of gene expression to mechanisms of genome evolution. GDCB has notable expertise in both experimental and computational approaches.

Cellular Biology: Molecular control of cellular structure and function

This includes the assembly and function of subcellular structures, channeling and compartmentalization of proteins and pathways, and regulation of metabolic networks, areas in which GDCB faculty have developed nationally recognized programs.

Development: Mechanisms of multicellular development

This includes study of the molecular mechanisms by which individual cells integrate and respond to intracellular and extracellular signals that determine developmental cell fate decisions. GDCB is building upon strengths in genome dynamics, functional genomics, and computational biology to achieve a nationally recognized research program in this area.

Computational Biology and Bioinformatics: Integration of computational approaches

This includes the development and use of sophisticated computational methods and technology to facilitate the effective use of the enormous amount of data generated in biological research. Faculty in GDCB are involved in the integration of computational approaches in all areas of research emphasis within the department.

Pedagogy: Instructional and pedagogical innovation

This includes development and implementation of novel and innovative methods and mechanisms to aid in student learning. Faculty in GDCB are especially active in the integration of web-based technology into both traditional face-to-face and on-line courses.

Metabolic Networking: Integration of metabolism into systems biology

This includes regulation of metabolic networks, metabolic regulation of gene expression and integration of metabolism into systems biology.