GDCB Seminar: Post-translational regulation of autophagy in Arabidopsis
Speaker: Diane Bassham, Walter E. and Helen Parke Loomis Professor of Plant Physiology in the Iowa State University Department of Genetics, Development and Cell Biology
Title: Post-translational regulation of autophagy in Arabidopsis
Abstract: Autophagy is a degradation pathway in which cellular components are transported to the vacuole to recycle nutrients or to clear damaged molecules and organelles. Autophagy therefore contributes to plant survival and growth during adverse environmental conditions. The process of autophagy begins with the formation of a double-membrane vesicle called an autophagosome, which encloses the cargo for degradation. The autophagosome fuses with the vacuole, releasing its cargo, which is then degraded. The resulting breakdown products are released back into the cytosol to maintain nutrient and energy homeostasis. Autophagy is active at a low level under normal conditions and is upregulated by many different environmental stresses. We have recently identified several factors that post-translationally regulate proteins involved in autophagy, and are analyzing their function in controlling stress tolerance.
Meeting link: https://iastate.webex.com/iastate/j.php?MTID=mb238d165439455f48123c9a3d116aef8