Speaker: Justin Walley, Iowa State University associate professor in plant pathology and microbiology and chair of bioinformatics and computational biology graduate program

Title: “Unraveling Signaling Networks using Integrated Omic Profiling”

Abstract: Proteins make or regulate nearly every component of a cell. Therefore, a comprehensive knowledge of proteomic states is essential for understanding biological systems. I will present my group's work at refining analytical and computational methods that enable deep coverage and high throughput quantification of proteins and post-translational modifications (phosphorylation, acetylation, ubiquitination, etc.). I will highlight our work on determining protein-protein interactions using proximity labeling as well as how we are using quantitative proteomics to reveal plant hormone response networks. Finally, I will discuss our work examining the maize innate immune response to the highly virulent fungal pathogen Cochliobolus carbonum. Specifically, this work focuses on how HC-toxin, a naturally occurring histone deacetylase inhibitor, promotes pathogen virulence towards maize.

Walley Lab: https://faculty.sites.iastate.edu/jwalley/

Dec. 10, 2021, GDCB Seminar flyer: Justin Walley