GDCB Seminar — 'Discovering auxin regulated phenotypes from proteotypes'
Speaker: Dior Kelley, assistant professor in genetics, development and cell biology
Title: “Discovering auxin regulated phenotypes from proteotypes”
Abstract: A hallmark feature of plant development is predictable, yet plastic, postembryonic organogenesis. Organ formation in plants occurs de novo from stem cell populations termed apical meristems that are present in the root and shoot. Our group is particularly interested in the hormone auxin, which comes from the Greek word “auxein” that means “to grow,” and it’s influence on plant morphogenesis. Decades of genetic studies in the model plant Arabidopsis (Arabidopsis thaliana) have defined key regulatory networks associated with root meristem properties, including hormones and gene regulation, but we are lacking such fundamental understanding in crops such as corn (Zea mays). In order to identify genetic drivers of hormone-regulated plant phenotypes we employ a novel integrated proteotype-to-phenotype approach that relies on quantitative proteomics and reverse genetic screens. This proteotype-centric method has allowed us to discover novel proteins that influence root morphogenesis in maize and Arabidopsis. Our current and proposed research programs will expand the molecular toolbox of plant growth regulators, generate large-scale open access phenomic datasets, and facilitate biological network discovery that is needed to inform agricultural strategies.
Host: Jeff Essner, professor in genetics, development and cell biology
Kelley lab: https://faculty.sites.iastate.edu/dkelley/