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GDCB Special Thursday Seminar: 'Deciphering auxin driven root development'

Dec 6, 2018 - 4:10 PM
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Dior KelleySpeaker: Dior Kelley, Iowa State University Department of Genetics, Development and Cell Biology Adjunct Assistant Professor

Title: Deciphering auxin driven root development

Abstract: Auxin is a major plant hormone that plays instructive roles in almost every aspect of plant biology, including cell growth and fate. Auxin perception involves the TIR1/AUXIN F-BOX (TIR1/AFB) family of ubiquitin E3 ligases and the Aux/IAA family of transcriptional regulators (Kelley and Estelle, 2012; Kelley, 2018). Auxin perception leads to ubiquitination and degradation of the Aux/IAAs and subsequently tightly regulated transcriptional changes that have been well documented (Weijers and Wagner, 2016). Depending on the context, auxin action can lead to different developmental outcomes. How this is achieved is not well understood. My research objective is to determine how auxin signaling modules control diverse developmental processes, with a particular emphasis on root stem cell maintenance. I plan to integrate systems-level profiling with genetic and molecular approaches to uncover and comprehensively characterize novel genes involved in auxin-dependent pathways. This includes research plans to (1) functionally characterize novel root meristem mutants we have identified from proteomics studies (2) examine the interplay between sugar signaling and auxin action in primary roots (3) define auxin-mediated networks derived from multi-scale omics profiling in primary maize roots.

Host: Diane Bassham