Schedule of Classes and Complete Iowa State University Catalog

Courses primarily for graduate students, open to qualified undergraduates:

GDCB 5100. Transmission Genetics.

(3-0) Cr. 3. F. Prereq: GEN 4100 or graduate standing
In-depth investigations of modern research practices of transmission genetics. Designed for students interested in genetic research. Topics include: Mendelian genetic analysis, analysis of genetic pathways, mutational analysis of gene function, chromosomal mechanics, genetic mapping, epigenetic inheritance, human genetic analysis.

GDCB 5110. Molecular Genetics.

(Cross-listed with MCDB). (3-0) Cr. 3. S. Prereq: BIOL 3130 and BBMB 4050
The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes.

GDCB 5130. Plant Metabolism.

(Cross-listed with PLBIO). (2-0) Cr. 2. Alt. F., offered even-numbered years. Prereq: BIOL 3300, PHYS 1110, CHEM 3310; one semester of biochemistry recommended
Photosynthesis, respiration, and other aspects of plant metabolism.

GDCB 5280. Advances in Molecular Cell Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: Courses in general cell biology and biochemistry
Cell biological processes including cell signaling, cell division, intracellular trafficking, biogenesis of organelles, cell adhesion and motility.

GDCB 5330. Advances in Developmental Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: BIOL 3140 or Biol 4230
Fundamental principles in multicellular development. Emphasis on cellular and molecular regulation of developmental processes, and experimental approaches as illustrated in the current literature.

GDCB 5360. Statistical Genetics.

(Cross-listed with STAT). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: STAT 4010, STAT 4470; GEN 3200 or BIOL 3130
Statistical models and methods for genetics covering models of population processes: selection, mutation, migration, population structure, and linkage disequilibrium, and inference techniques: genetic mapping, linkage analysis, and quantitative trait analysis. Applications include genetic map construction, gene mapping, genome-wide association studies (GWAS), inference about population structure, phylogenetic tree construction, and forensic and paternity identification.

GDCB 5420. Introduction to Molecular Biology Techniques.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification
Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420A. Introduction to Molecular Biology Techniques: DNA Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification
Includes genetic engineering procedures, sequencing, PCR, and genotyping. Offered on a satisfactory-fail basis only.

GDCB 5420C. Introduction to Molecular Biology Techniques: Cell Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S. Prereq: Graduate classification
Includes immunophenotyping, ELISA, flow cytometry, microscopic techniques, image analysis, confocal, multiphoton and laser capture microdissection. Offered on a satisfactory-fail basis only.

GDCB 5420D. Introduction to Molecular Biology Techniques: Plant Transformation.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification
Includes Agrobacterium and particle gun-mediated transformation of tobacco, Arabidopsis, and maize, and analysis of tranformants. Offered on a satisfactory-fail basis only.

GDCB 5420E. Introduction to Molecular Biology Techniques: Proteomics..

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F. Prereq: Graduate classification
Includes two-dimensional electrophoresis, laser scanning, mass spectrometry, and database searching. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420F. Introduction to Molecular Biology Techniques: Metabolomics.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification
Metabolomics and the techniques involved in metabolite profiling. For non-chemistry majoring students who are seeking analytical aspects into their biological research projects. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420G. Introduction to Molecular Biology Techniques: Genomic.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification
Offered on a satisfactory-fail basis only.

GDCB 5440. Introduction to Bioinformatics.

(Cross-listed with BCB, COM S, CPR E). (4-0) Cr. 4. F. Prereq: MATH 1650 or STAT 4010 or equivalent
Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative, functional genomics, and systems biology.

GDCB 5450. Plant Molecular, Cell and Developmental Biology.

(Cross-listed with MCDB, PLBIO). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: Biol 313, BIOL 314, BIOL 330 or BBMB 405
Plant nuclear and organelle genomes; regulation of gene expression; hormone signaling; organization, function, and development of plant cells and subcellular structures; regulation of plant growth and development.

GDCB 5560. Cellular, Molecular and Developmental Neuroscience.

(Cross-listed with B M S, NEURO). (3-0) Cr. 3. F. Prereq: BIOL 3350 or BIOL 4360; physics recommended
Fundamental principles of neuroscience including cellular and molecular neuroscience, nervous system development, sensory, motor and regulatory systems.

GDCB 5570. Rotations in Neuroscience.

(Cross-listed with NEURO). (2-0) Cr. 2. Alt. S., offered odd-numbered years. Prereq: Neuro 5560or equivalent course
Research methods and techniques; exercises and/or demonstrations representing individual faculty specialties.

GDCB 5680. Statistical Bioinformatics.

(Cross-listed with BCB, COM S, STAT). (3-0) Cr. 3. S. Prereq: BCB 5670, BBMB 3010, BIOL 3150, STAT 4300, credit or enrollment in GEN 4110
Advanced sequence models. Basic methods in molecular phylogeny. Hidden Markov models. Genome annotation. DNA and protein motifs. Introduction to gene expression analysis.

GDCB 5700. Systems Biology. 

(Cross-listed with BCB, COM S, CPR E, STAT). (3-0) Cr. 3. S. Prereq: BCB 5670, BIOL 3150, COM S 3110 and either 2080 or 2280, GEN 4110, STAT 4300
Algorithmic and statistical approaches in computational functional genomics and systems biology. Elements of experiment design. Analysis of high throughput gene expression, proteomics, and other datasets obtained using system-wide measurements. Topological analysis, module discovery, and comparative analysis of gene and protein networks. Modeling, analysis, simulation and inference of transcriptional regulatory modules and networks, protein-protein interaction networks, metabolic networks, cells and systems: Dynamic systems, Boolean, and probabilistic models. Multi-scale, multi-granularity models. Ontology-driven, network based, and probabilistic approaches to information integration.

GDCB 5900. Special Topics.

Cr. arr. Repeatable. Prereq: Permission of instructor

Courses for graduate students:

GDCB 6610. Advanced Topics in Neuroscience.

(Cross-listed with BBMB, NEURO). (2-0) Cr. 2-3. Repeatable. Alt. S., offered even-numbered years. Prereq: NEURO 5560 (or comparable course) or permission of instructor
Topics may include molecular and cellular neuroscience, neurodevelopment, neuroplasticity, neurodegenerative diseases, cognitive neuroscience, sensory biology, neural integration, membrane biophysics, neuroethology, techniques in neurobiology and behavior.

GDCB 6900. Seminar in GDCB.

Cr. 1. Repeatable.
Research seminars by faculty, invited speakers, and graduate students. Offered on a satisfactory-fail basis only.\

GDCB 6960. Research Seminar.

(Cross-listed with AGRON, BBMB, FOR, HORT, PLBIO). Cr. 1. Repeatable.
Research seminars by faculty and graduate students. Offered on a satisfactory-fail basis only.

GDCB 6980. Seminar in Molecular, Cellular, and Developmental Biology.

(Cross-listed with BBMB, MCDB, MICRO, V MPM). (2-0) Cr. 1-2. Repeatable. F.S.
Student and faculty presentations.

GDCB 6990. Research.

Cr. arr. Repeatable.
Research for thesis or dissertation. Offered on a satisfactory-fail basis only.