Dr. Kelley, Assistant Professor, received her B.S. in Chemistry from the University of California Santa Cruz in 2000, and her Ph.D. in Plant Biology from the University of California Davis in 2009. Dr. Kelley joined GDCB in January 2015.
Auxin is a major plant hormone that plays instructive roles in almost every aspect of plant biology, including cell growth and fate. Depending on the context, auxin action can lead to different developmental outcomes. How this is achieved is not well understood. My research program explores how auxin signaling modules control diverse developmental processes in Arabidopsis. I am applying a variety of molecular approaches to these studies, including RNA-seq, Ribo-seq, proteomics and phenotyping. Such multi-scale integration will elucidate new aspects of auxin biology, including links between different aspects of gene regulation and identify novel regulators of plant development.
- Clark, N.M., Shen, Z., Briggs, S. P., Walley, J.W., Kelley, D.R. (2019) Auxin Induces Widespread Proteome Remodeling in Arabidopsis seedlings. Proteomics first published 05 August 2019: https://doi.org/10.1002/pmic.201900199 Vol 19, Issue 17, Sept 2019 1900199 (Cover Article).
- Pu, Y., Walley, J.W., Shen, Z., Lang, M.* Briggs, S. P., Estelle, M., Kelley, D.R. (2019) Quantitative early auxin root proteomics identifies GAUT10, a galacturonosyltransferase, as a novel regulator of root meristem maintenance. Molecular and Cellular Proteomics March 27, 2019, mcp.RA119.001378; https://doi.org/10.1074/mcp.RA119.001378. (Cover Article) *Undergraduate researcher
- Kelley, D.R. E3 ubiquitin ligases: key regulators of hormone signaling in plants. (2018) Invited review, Molecular and Cellular Proteomics 17 (6): 1047-1054. DOI: https://doi.org/10.1074/mcp.MR117.000476.
- Kelley, D.R.*, Shen, Z., Walley, J.W., Chapman, E.J., Briggs, S. P., Estelle, M.* (2017) Quantitative proteomic analysis of auxin signaling during seedling development. bioRxiv: doi.org/10.1101/211532. *Corresponding Author
- Gilkerson J., Kelley D.R., Tam R., Estelle M., and Callis J. (2015) Lysine residues are not required for proteasome-mediated proteolysis of the Aux/IAA protein IAA1. Plant Physiology, published online before print April 2015. DOI: https://doi.org/10.1104/pp.15.00402.
- Kelley, D.R. and Estelle, M. (2012) Ubiquitin-mediated control of plant hormone signaling. Plant Physiology 160(1): 47-55.
- Kelley, D.R., Arreola, A., Gallagher, T., and Gasser, C.S. (2012) ETTIN (ARF3) physically interacts with KANADI proteins to form a functional complex essential for integument development and polarity determination in Arabidopsis. Development 139(6): 1105-9.
- Walley, J.W., Kelley, D.R., Savchenko, T., and Dehesh, K. (2010) Investigating the function of CAF1 deadenylases during plant stress responses. Plant Signal Behav. 5(7):802-5.
- Walley, J.W., Kelley, D.R., Nestorova G, Hirschberg D, Dehesh, K. (2010) Arabidopsis deadenylases AtCAF1a and AtCAF1b mediate response to environmental stress. Plant Physiology 152(2): 866-75.
- Kelley, D.R., and Gasser, C.S. (2009) Ovule Development: Genetic Trends and Evolutionary Considerations. Sexual Plant Reproduction 22(4): 229-34.
- Kelley, D.R., Skinner, D, and Gasser, C.S. (2009) Roles of polarity determinants in ovule development. The Plant Journal 57(6): 1054-64. (Cover article).
- Kaothien, P., Ok, S.H., Shuai, B., Wengier, D., Cotter, R., Kelley, D.R., Kiriakopolos, S., Muschietti, J., and McCormick, S. (2005) Kinase partner protein interacts with the LePRK1 and LePRK2 receptor kinases and plays a role in polarized pollen tube growth. The Plant Journal 42 (4): 492-503.
- Tang, W.H., Kelley, D.R., Ezcurra, I., Cotter, R., and McCormick, S. (2004) LeSTIG1, an extracellular binding partner for the pollen receptor kinases LePRK1 and LePRK2, promotes pollen tube growth in vitro. The Plant Journal 39(3): 343-53.