My research focus is on receptor kinase FERONIA-mediated signaling in Arabidopsis thaliana. FERONIA is involved in many aspects of a plant’s life, such as reproduction, root development, vegetative growth and responses to abiotic and biotic stresses. We are using genetic, genomic, proteomic, molecular and biochemical approaches and network construction to try to understand the molecular mechanisms through which FERONIA receptor kinase regulates plant growth and stress in response to different environmental conditions.
Guo H* et al. 2020. Integrated Omics Reveal Novel functions of FERONIA Receptor Kinase in Arabidopsis thaliana, in submission (*co-corresponding author)
Guo H*, Yin, Y. 2019. Measuring protein half-life in Arabidopsis thaliana. Bio-Protocol 9 (15) : e3318. (*corresponding author)
Hansen RL, Guo H, Yin Y, Lee, YJ. 2019. High-throughput Lipid Screening Discovers Arabidopsides as Biomarkers of FERONIA in Arabidopsis thaliana. The Plant Journal. 97(2): 341-351.
Guo H*, Nolan T, Song G, Liu S, Xie, Z., Chen, J., Schnable, P., Walley, J and Yin, Y*. 2018. Feronia receptor kinase contributes to plant immunity by suppressing Jasmonic acid signaling. Current Biology. 28: 3316-3324.
(* co-corresponding author)
(News release: https://www.news.iastate.edu/news/2018/10/24/feronia)
Nolan, T., Liu, S., Guo, H., Li, L., Schnable, S. & Yin, Y. 2017. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by Highthroughput Sequencing (ChIPseq) and RNAseq. Method in Molecular Biology. 1564: 63-79.
Ye, H., Liu, S., Tang, B., Nolan. T., Xie, Z., Chen, J., Schulte, R., Guo, H., Li, Z., Aluru, M., Aluru, S., Schnable, P., Yin, Y. 2017. RD26 mediates the crosstalk between drought and Brassinosteroid signaling pathway. Nature Communications. 8:14753
Chockalingam, S. P., Aluru, M., Guo, H., Yin, Y., Aluru, S. 2017. Reverse Engineering Gene Networks: A Comparative Study at Genome-scale. The 8th ACM International Conference. DOI: 10.1145/3107411.3107428.
Deng XG, Zhu T, Peng XJ, Xi DH, Guo H, Yin Y, Zhang DW, Lin HH. 2016. Role of brassinosteroid signaling in modulating Tobacco mosaic virus resistance in Nicotiana benthamiana. Sci Rep. 6:20579.
Wang, X., Chen J., Xie, Z., Liu, S., Nolan, T., Ye, H., Zhang, M., Guo, H., Schnable, P.S., Li, Z. and Yin, Y. 2014. Histone Lysine Methyltransferase SDG8 Is Involved in Brassinosteroid Regulated Gene Expression in Arabidopsis thaliana. Molecular Plant. 7: 1303-1315.
Zhang, D., Ye, H, Guo, H., Johnson, A., Zhang, M., Lin, H, and Yin, Y. 2014. Transcription Factor HAT1 is Phosphorylated by BIN2 Kinase and Mediates Brassinsteroid Repressed Gene Expression in Arabidopsis. Plant J. 77: 59-70.
Zhang, D., Ye, H, Guo, H., Johnson, A., Zhang, M., Lin, H, and Yin, Y. 2014. Transcription factors involved in brassinosteroid repressed gene expression and their regulation by BIN2 kinase. Plant Signal Behav. 9: e27849
Guo H, Li L, Aluru M, Aluru S, Yin Y. 2013. Mechanisms and networks for brassinosteroid regulated gene expression. Curr Opin Plant Biol. 16:545-53.
Ye, H., Li, L., Guo, H., Yin Y. 2012. MYBL2 is a substrate of GSK3-like kinase BIN2 and acts as a corepressor of BES1 in brassinosteroid signaling pathway in Arabidopsis. Proc Natl Acad Sci U S A. 109: 20142-20147.
Yu, X., Li, L., Zola, J., Aluru, M., Ye, H., Foudree, A., Guo, H., Anderson, S., Aluru, S., Liu, P., Rodermel, S., and Yin, Y. 2011. A Brassinosteroid transcriptional network revealed by genome-wide identification of BES1 target genes in Arabidopsis thaliana. Plant J. 65: 634-646
Li, L., Ye, H, Guo, H., Yin Y. 2010. Arabidopsis IWS1 interacts with transcription factor BES1 and is involved in Brassinosteroid regulated gene expression. Proc Natl Acad Sci U S A. 107:3918-3923
Guo, H, Li, L, Ye, H, Yu, X, Algreen, A, Yin Y. 2009. Three Related Receptor-Like Kinases Are Required for Optimal Cell Elongation in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 106: 7648-7653
Guo, H., Ye, H., Li, L.,Yin Y. 2009. A family of Receptor-Like Kinases are regulated by BES1 and involved in plant growth in Arabidopsis thaliana. Plant Signaling & Behavior. 4: 784-786