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Ph.D. Defense (Christian Montes Serey) — 'Identifying novel candidates involved in brassinosteroids and autophagy cross-regulation'

Nov 7, 2022 - 2:00 PM
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Speaker: Christian Montes Serey, graduate student in Plant Pathology, Entomology, and Microbiology

Title: "Identifying novel candidates involved in brassinosteroids and autophagy cross-regulation"

Abstract: Understanding how plants adapt to stress conditions, the many molecular networks being modulated, and the growth tradeoff they take is one our overarching goals. The steroidal hormone brassinosteroids (BRs) and the Target of Rapamycin complex (TORC) are two important plant growth and stress regulation hubs and, as such, they modulate intricate signaling networks to exert their functions. By studying they key BR negative regulator BRASSINOSTEROID INSENSITIVE 2 (BIN2) and TORC subunit RAPTOR1B through a multi-omics perspective, I was able to reconstruct an integrative network that captured different layers of interactions (transcript expression and protein abundance or phosphorylation) and provided a dataset (kinase targets and transcription factor targets) of events happening when BIN2 or RAPTOR1B were misexpressed. Using this data, I was able to identify novel genes involved in brassinosteroid response and TORC-mediated autophagy.

Webex link: https://iastate.webex.com/iastate/j.php?MTID=m60242959fd9b6bfab0def4572aaa7316

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Meeting number (access code): 2624 007 1625

Meeting password: mHwyxQ2Jt38