Courses primarily for undergraduate students

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Biol 211 Lab
Biology 211L

Links to: Schedule of Classes and Complete Iowa State University Catalog

Bioinformatics and Computational Biology

BCBIO 110. BCBIO Orientation.

(1-0) Cr. 0.5. F.

First 8 weeks. Orientation to the area of bioinformatics and computational biology. For students considering a major in BCBIO. Specializations and career opportunities. Offered on a satisfactory-fail basis only.

BCBIO 211. Introduction to Bioinformatics and Computational Biology.

(3-0) Cr. 3. S.

Perl programming, molecular biology, biological databases, sequence alignment, homology search, identification of sequence patterns, construction of phylogenetic trees, gene function prediction, gene structure prediction, genomic annotation and comparative genomics.

BCBIO 401. Fundamentals of Bioinformatics and Computational Biology I.

(3-0) Cr. 3. F. Prereq: BCBIO 211 and basic programming experience (e.g. COM S 207, COM S 208, COM S 227 or permission of instructor)

Application of computer science to molecular biology. String algorithms, sequence alignments, indexing data structures, homology search methods, pattern recognition, fragment assembly, genome annotation, construction of bioinformatics databases, and gathering and distribution of biological information with the Internet.

BCBIO 402. Fundamentals of Bioinformatics and Computational Biology II.

(3-0) Cr. 3. S. Prereq: BCBIO 401

Genomics: Gene structure prediction, gene function prediction and comparative genomics. Post-genomics: Gene expression studies, DNA microarrays, next-generation sequencing of transcriptome. Structural biology: Protein and RNA structure predictions, structure representation, comparison and visualization. Systems biology: Signal transduction pathway inference, biological networks and systems.

BCBIO 442. Bioinformatics and Computational Biology Techniques.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 442A. Bioinformatics and Computational Biology Techniques: Sequence Database Searching.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 442B. Bioinformatics and Computational Biology: Protein Structure Databases, Visualization, and Prediction.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 442C. Bioinformatics and Computational Biology Techniques: Phylogenetic Analysis.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 442D. Bioinformatics and Computational Biology Techniques: Microarray Analysis.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 444. Introduction to Bioinformatics.

(Cross-listed with BCB, BIOL, COM S, CPR E, GEN). (4-0) Cr. 4. F. Prereq: MATH 165 or STAT 401 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative and functional genomics, systems biology.

BCBIO 490. Independent Study.

Cr. 1-5. Repeatable, maximum of 9 credits. F.S.SS. Prereq: BCBIO 211, junior or senior classification, permission of instructor

Students in the College of Liberal Arts and Sciences may use no more than 9 credits of BCBIO 490 and 491 toward graduation.

BCBIO 491. Team Research Projects.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: BCBIO 211, junior or senior classification, permission of instructor

Research projects in bioinformatics and computational biology done by teams of students. Students in the College of Liberal Arts and Sciences may use no more than 9 credits of BCBIO 490 and 491 toward graduation.

Biology

BIOL 101. Introductory Biology.

(3-0) Cr. 3. F.S.SS.

Life considered at cellular, organism, and population levels. Function and diversity of the living world. Presentation of basic biological principles as well as topics and issues of current human interest. Does not satisfy biology major requirements.

BIOL 110. Introduction to Biology.

Cr. 1. F.

Orientation to the scope of the biological sciences, and discussion of professional opportunities. Required of first year biology majors. Offered on a satisfactory-fail basis only.

BIOL 111. Opportunities in Biology.

(1-0) Cr. 0.5. S.

Introduction to biological science disciplines and professional opportunities through faculty presentations which examine a variety of current research topics. Offered on a satisfactory-fail basis only.

BIOL 112. Transfer Student Orientation.

Cr. R. F.S.

Orientation to opportunities in Biology. Review of degree requirements and other information needed by students that have not participated in the first year Biology orientation courses. Offered on a satisfactory-fail basis only.

BIOL 155. Human Biology.

(3-0) Cr. 3. F.S.

A survey course of human biology, including principal structures and functions of the body systems and the diseases and disorders associated with them. Designed to meet general education requirements in natural science. Not recommended for those seeking a career in the allied health professions or for students majoring in life science. Does not satisfy biology major requirements.

BIOL 173. Environmental Biology.

(Cross-listed with ENV S). (3-0) Cr. 3. F.S.

An introduction to the structure and function of natural systems at scales from the individual to the biosphere and the complex interactions between humans and their environment. Discussions of human population growth, biodiversity, sustainability, resource use, and pollution. Does not satisfy biology major requirements.

BIOL 201. Introduction to Environmental Issues.

(Cross-listed with ENSCI, ENV S). (2-0) Cr. 2. F.S.

Discussion of current and emerging environmental issues such as human population growth, energy use, loss of biodiversity, water resources, and climate change.

BIOL 204. Biodiversity.

(Cross-listed with ENV S). (4-0) Cr. 2. S. Prereq: One course in life sciences

Survey of the major groups of organisms and biological systems. Definition, measurements, and patterns of distribution of organisms. Sources of information about biodiversity. Does not satisfy biology major requirements. Half semester course.

BIOL 211. Principles of Biology I.

(3-0) Cr. 3. F.S. Prereq: High school biology

Introduction to the nature of life, including the diversity of microbial, plant, and animal life; the nature of heredity; evolution; and principles of ecology. Intended for life science majors.

BIOL 211L. Principles of Biology Laboratory I.

(0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 211

Laboratory to accompany 211.

BIOL 212. Principles of Biology II.

(3-0) Cr. 3. F.S. Prereq: High School Biology; high school chemistry or credit or enrollment in CHEM 163 or CHEM 177

Introduction to the chemical, molecular, and cellular basis of life; form and function of microbial, plant, and animal life. Intended for life science majors.

BIOL 212L. Principles of Biology Laboratory II.

(0-3) Cr. 1. F.S. Prereq: credit or enrollment in BIOL 212

Laboratory to accompany 212.

BIOL 251. Biological Processes in the Environment.

(Cross-listed with ENSCI). (3-0) Cr. 3. S.

Plant and microbial processes in environmental systems including their interactions with human activities.

BIOL 255. Fundamentals of Human Anatomy.

(3-0) Cr. 3. F. Prereq: High School Biology and Chemistry, or BIOL 101

An introduction to human anatomy, beginning with cells and tissues, surveying all body systems, relating form to function. Systems covered include: integumentary, bones and joints, muscles, nervous, sensory, endocrine, circulatory, lymphatic, respiratory, digestive, urinary, and reproductive. Pre-Medical students should consider Biol 351 for their anatomy background. Does not satisfy biology major requirements.

BIOL 255L. Fundamentals of Human Anatomy Laboratory.

(0-3) Cr. 1. F. Prereq: Credit or enrollment in BIOL 255

Investigation of human anatomy using models and dissections of preserved organs and model mammals. Pre-Medical students should consider 351 for their anatomy background. Does not satisfy biology major requirements.

BIOL 256. Fundamentals of Human Physiology.

(3-0) Cr. 3. S. Prereq: High School Biology and Chemistry, or BIOL 101, or BIOL 255 (recommended)

An introduction to human physiology, studying the function of all body systems. Systems covered include: integumentary, bones and joints, muscles, nervous, sensory, endocrine, circulatory, lymphatic and immune, respiratory, digestive, urinary, and reproductive. Pre-Medical students should consider 335 for their physiology background. Does not satisfy biology major requirements.

BIOL 256L. Fundamentals of Human Physiology Laboratory.

(0-3) Cr. 1. S. Prereq: Credit or enrollment in BIOL 256

Student-conducted experiments investigating concepts of human physiology with computer data acquisition and analysis. Interpretation of experimental results and preparation of lab reports. Pre-Medical students should consider 335 for their anatomy and physiology background. Does not satisfy biology major requirements.

BIOL 258. Human Reproduction.

(Cross-listed with W S). (3-0) Cr. 3. F. Prereq: BIOL 101, or BIOL 155, or BIOL 211

Anatomy and physiology of human reproductive systems, including fertility, pregnancy, and delivery. Does not satisfy biology major requirements.

BIOL 306. Metabolic Physiology of Mammals.

Cr. 3. Prereq: BIOL 211, BIOL 212

Introduction to physiology of metabolic function in mammals and other animals. Metabolic processes and their interactions with various subsystems, approached form an organismal perspective. Integration of cellular, gastrointestinal, cardiovascular, respiratory, and renal processes, relevant to their control and integration at the nervous and endocrine system levels. Functional aspects of organismal physiology; energy and water balances, physiology of rest exercise, and environmental stress. Students cannot receive credit for both Biol 306 and Biol 335.

BIOL 307. Women in Science and Engineering.

(Cross-listed with W S). (3-0) Cr. 3. F. Prereq: a 200 level course in science, engineering or women’s studies; ENGL 250

The interrelationships of women and science and engineering examined from historical, sociological, philosophical, and biological perspectives. Factors contributing to under-representation; feminist critiques of science; examination of successful strategies. Does not satisfy biology major advanced credit requirements.

Meets U.S. Diversity Requirement

BIOL 312. Ecology.

(Cross-listed with A ECL, ENSCI). (3-3) Cr. 4. F.SS. Prereq: BIOL 211L and BIOL 212L

Fundamental concepts and principles of ecology dealing with organisms, populations, communities and ecosystems. Laboratory and field exercises examine ecological principles and methods as well as illustrate habitats.

BIOL 313. Principles of Genetics.

(Cross-listed with GEN). (3-0) Cr. 3. F.S.SS. Prereq: BIOL 211, BIOL 211L, BIOL 212, and BIOL 212L

Introduction to the principles of transmission and molecular genetics of plants, animals, and bacteria. Recombination, structure and replication of DNA, gene expression, cloning, quantitative and population genetics. Students may receive graduation credit for no more than one of the following: Gen 260, Gen 313 and 313L, Gen 320, Biol 313 and 313L, and Agron 320.

BIOL 313L. Genetics Laboratory.

(Cross-listed with GEN). (0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 313

Laboratory to accompany 313. Students may receive graduation credit for no more than one of the following: Biol 313 and 313L, Gen 260, Gen 313, Gen 320, and Agron 320.

BIOL 314. Principles of Molecular Cell Biology.

(3-0) Cr. 3. F.S. Prereq: BIOL 211, 211L, 212, 212L.

Integration of elementary principles of metabolism, bioenergetics, cell structure and function to develop a molecular view of how the cell works.

BIOL 315. Biological Evolution.

(3-0) Cr. 3. F.S. Prereq: BIOL 211, BIOL 211L, BIOL 212, BIOL 212L. Biol 313 recommended.

The mechanisms of evolution. Topics in microevolution: population genetics, natural selection, genetic variation, and adaptation. Macroevolution: speciation, extinction, phylogeny, and major evolutionary patterns.

BIOL 328. Molecular and Cellular Biology of Human Diseases.

Cr. 3. Prereq: BIOL 212

Survey of molecular, genetic and cellular aspects of human diseases. Fundamental concepts of cell biology and how they are linked to the pathologies of different classes of human diseases. Recent scientific advances with an emphasis on new methods of diagnosis and treatment.

BIOL 330. Principles of Plant Physiology.

(3-0) Cr. 3. Prereq: BIOL 313 or GEN 320; BIOL 314 or BBMB 301; CHEM 231 or CHEM 332; PHYS 106 or PHYS 111

An overview of classical and current concepts, principles and approaches regarding the basic mechanisms of plant function underlying growth, development and survival of plants. Topics covered include environmental and developmental signals, plant hormone action, signal transduction, mineral nutrition, water relations, metabolism and photosynthesis.

BIOL 330L. Principles of Plant Physiology Laboratory.

(0-3) Cr. 1. Prereq: Credit or enrollment in BIOL 330

Laboratory to accompany Biol 330. Experiments and explorations illustrating fundamental principles of plant physiology.

BIOL 335. Principles of Human and Other Animal Physiology.

(3-3) Cr. 4. F.S. Prereq: BIOL 314

Introduction to systemic functions with emphasis on mammals.

BIOL 336. Ecological and Evolutionary Animal Physiology.

Cr. 3. Prereq: BIOL 211, BIOL 212

Study of mechanisms by which animals perform life-sustaining functions; the evolution and adaptive significance of physiology traits, the diversity of physiological mechanisms, and how physiology and ecology interact.

BIOL 350. Comprehensive Human Anatomy.

(3-0) Cr. 3. F. Prereq: Credit in BIOL 211 and BIOL 212

Comprehensive survey of human anatomy, emphasizing structural and functional relationships of major organ systems. Compartmental study of normal anatomy; practical clinical application of anatomical regions.

BIOL 351. Comparative Chordate Anatomy.

(3-4) Cr. 5. S. Prereq: BIOL 212, junior classification

The evolution of chordates as reflected in the anatomy of extinct and living forms. Lecture topics include the history and diversity of chordates; comparisons of anatomic structures among major groups, the adaptive significance of anatomic structures. Laboratory involves dissection of representative species.

BIOL 352. Vertebrate Histology.

(3-3) Cr. 4. S. Prereq: BIOL 212

Microscopic structure of vertebrate tissues and organs, with an introduction to histological techniques.

BIOL 353. Introductory Parasitology.

(Cross-listed with MICRO, V PTH). (3-3) Cr. 4. S. Prereq: BIOL 212

Biology and host-parasite relationships of major groups of animal parasites, and techniques of diagnosing and studying parasites.

BIOL 354. Animal Behavior.

(3-0) Cr. 3. F. Prereq: BIOL 212

Ethological and sociobiological approaches to animal behavior. Genetic and developmental aspects of behavior, biological rhythms, orientation (including navigation, migration), communication, and social behavior (mating, aggression, parental care).

BIOL 354L. Laboratory in Animal Behavior.

(0-3) Cr. 1. F. Prereq: Credit or enrollment in BIOL 354

Laboratory techniques for observation, description and analysis of animal activities; independent projects.

BIOL 355. Plants and People.

(3-0) Cr. 3. S. Prereq: Credit in BIOL 211 and BIOL 211L

Uses of plants and fungi by humans and the importance of plants in the past, present and future. Discussion of fruits, vegetables, grains, herbs, spices, beverages, oils, fibers, wood, medicines, and drugs, in the context of their agricultural, cultural, and economic roles in modern societies. Emphasis on origins and worldwide diversity of culturally important plants, their characteristics, and uses.

BIOL 356. Dendrology.

(Cross-listed with FOR). (2-4) Cr. 4. F. Prereq: BIOL 211

Identification and ecology of North American woody plant species. Importance of woody plants in timber production and wildlife habitat. Natural disturbances, human impacts, management and restoration concerns for major North American forest regions will be addressed.

BIOL 364. Invertebrate Biology.

Cr. 3-4. F. Prereq: BIOL 212

Emphasis on diversity, development, physiology and behavior of invertebrate organisms- the “spineless wonders” of the world. Laboratory involves hands-on study and investigation of living invertebrates.

BIOL 365. Vertebrate Biology.

(Cross-listed with A ECL). (3-2) Cr. 4. F. Prereq: BIOL 212, BIOL 212L

Evolution, biology, and classification of fish, amphibians, reptiles, birds, and mammals. Emphasis on a comparative analysis of the structure and function of organ systems. Laboratory exercises concentrate on morphology and identification of orders of vertebrates.

BIOL 366. Plant Systematics.

(2-4) Cr. 4. S. Prereq: BIOL 211

Introduction to plant phylogenetic systematics, plant classification, survey of flowering plant families, identification and field study of local plants.

BIOL 371. Ecological Methods.

(Cross-listed with A ECL). (2-3) Cr. 3. F. Prereq: A ECL 312; STAT 101 or STAT 104

Quantitative techniques used in management of natural resources with emphasis on inventory and manipulation of habitat and animal populations.

BIOL 381. Environmental Systems I: Introduction to Environmental Systems.

(Dual-listed with EEOB 581). (Cross-listed with ENSCI, ENV S, MICRO). Cr. 3-4. F. Prereq: 12 credits of natural science including biology and chemistry

Introduction to the structure and function of natural environmental systems. Emphasis on the analysis of material and energy flows in natural environmental systems and the primary environmental factors controlling these systems.

BIOL 382. Environmental Systems II: Analysis of Environmental Systems.

(Dual-listed with EEOB 582). (Cross-listed with ENSCI). (2-2) Cr. 3. S. Prereq: ENSCI 381

Continuation of EnSci 381. Systems approach to the analysis of material and energy flows in natural environmental systems and the primary environmental factors controlling these systems.

BIOL 393. North American Field Trips in Biology.

Cr. 1-4. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, usually during break periods, to North American locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule.

BIOL 393A. North American Field Trips in Biology: Pre-trip Seminar.

(1-0) Cr. 1. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Discussion of relevant biological and cultural topics during semester preceding extended field trips to North American locations of interest to biologists.

BIOL 393B. North American Field Trips in Biology: North American Field trip.

Cr. 1-3. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trip to North American location under supervision of faculty member, usually during break periods, to North American locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule. Report required.

BIOL 394. International Field Trips in Biology.

Cr. 1-4. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, usually during break periods, to international locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule.

Meets International Perspectives Requirement.

BIOL 394A. International Field Trips in Biology: Pre-trip Seminar.

(1-0) Cr. 1. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Discussion of relevant biological and cultural topics during semester preceding extended field trip to international locations of interest to biologists.

BIOL 394B. International Field Trips in Biology: Field Trip to International Location.

Cr. 1-3. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, under supervision of faculty member, usually during break periods, to international locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule. Offered on a satisfactory-fail basis only.

BIOL 402. Introduction to Pathology.

(Cross-listed with V PTH). (3-0) Cr. 3. S. Prereq: BIOL 211 and BIOL 212 with labs

Introductory exploration of pathology as a medical discipline. This includes study of disease mechanisms via an introduction to general pathology topics (cell degeneration, necrosis, disturbances of growth, disturbances of blood flow, inflammation, neoplasia) and organ system-specific response to injury.

BIOL 414. Life History and Reproductive Strategies.

(Dual-listed with EEOB 514). (3-0) Cr. 3. F. Prereq: BIOL 315 or equivalent; course in population ecology suggested.

Evolution of ecological adaptations at the individual, population, community and landscape levels. Emphasis is on evolutionary mechanisms and adaptive strategies; units and mechanisms of evolution, life history strategies, species interactions and organization of communities, behavior, and patterns of distribution, speciation and macroevolution.

BIOL 423. Developmental Biology.

(3-0) Cr. 3. S. Prereq: BIOL 313

Principles of embryogenesis and animal development. Establishment of body axes, organ and limb development, and specification of cell fates. Emphasis on cell signaling and the control of gene expression within the context of a developing organism. Medically relevant subjects will be discussed, including stem cells, cancer biology, fertilization, and cloning.

BIOL 423L. Developmental Biology Laboratory.

(0-3) Cr. 1. S. Prereq: Credit or enrollment in BIOL 423

Experiments and explorations illustrating fundamental principles of multicellular development.

BIOL 428. Topics in Cell Biology.

(3-0) Cr. 3. S. Prereq: BIOL 314

Selected topics on biological organization and function at the cellular level. Emphasis on biomembranes.

BIOL 434. Endocrinology.

(Dual-listed with EEOB 534). (3-0) Cr. 3. S. Prereq: BIOL 211, BIOL 212

Chemical integration of vertebrate organisms. The structure, development, and evolution of the endocrine glands and the function and structure of their hormones.

BIOL 436. Neurobiology.

(3-0) Cr. 3. F. Prereq: BIOL 212

Basic principles of brain function and development. Signaling of nerve cells, synaptic transmission, structure/function of ion channels and receptors, memory and synaptic plasticity, movement and central control, sensation and sensory processing, construction of neural circuits, early brain development, complex brain functions in health and disease.

BIOL 439. Environmental Physiology.

(Dual-listed with EEOB 539). Cr. 3-4. Alt. S., offered even-numbered years. Prereq: BIOL 335; physics recommended

Physiological adaptations to the environment with an emphasis on vertebrates.

BIOL 444. Introduction to Bioinformatics.

(Dual-listed with EEOB 544). (Cross-listed with BCB, BCBIO, COM S, CPR E, GEN). (4-0) Cr. 4. F. Prereq: MATH 165 or STAT 401 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative and functional genomics, systems biology.

BIOL 451. Plant Evolution and Phylogeny.

(Dual-listed with EEOB 551). (3-3) Cr. 4. F. Prereq: BIOL 315 or equivalent.

Survey of land plant evolution; phylogenetic comparison of anatomical, reproductive, and life history specializations. Relationships among bryophytes, lycophytes, pteridophytes, gymnosperms, and angiosperms emphasizing significant evolutionary changes documented by paleobotanical, morphological, and molecular studies.

BIOL 454. Plant Anatomy.

(3-3) Cr. 4. F. Prereq: BIOL 212L; BIOL 366 recommended

Characteristics of cell and tissue types in vascular plants. Anatomy of developing and mature stems, roots, and leaves, including secondary (woody) growth. Introduction to the special anatomy of flowers and seeds.

BIOL 455. Bryophyte and Lichen Biodiversity.

(Dual-listed with EEOB 555). Cr. 3. Prereq: BIOL 211, BIOL 211L

Introduction to the biology and ecology of mosses, liverworts, and lichens. Emphasis on identification and diversity of local representatives of these three groups of organisms. Required field trips and service-learning.

BIOL 456. Principles of Mycology.

(Cross-listed with MICRO). (2-3) Cr. 3. F. Prereq: 10 credits in biological sciences

Morphology, diversity and ecology of fungi; their relation to agriculture and industry and human health.

BIOL 457. Herpetology.

(Cross-listed with A ECL). (2-0) Cr. 2. F. Prereq: BIOL 351 or BIOL 365

Biology, ecology, and evolution of amphibians (salamanders, frogs, caecilians) and reptiles (lizards, snakes, tuatara, turtles, crocodilians). Emphasis on structure, physiological adaptation to different environments, behavior, reproduction, roles of amphibians and reptiles in ecosystems, and conservation. Laboratory focus on survey methods, identification, relationships, distribution, habits, and habitats of amphibians and reptiles.

BIOL 457L. Herpetology Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. F. Prereq: BIOL 351 or BIOL/A ECL 365; concurrent registration in BIOL 457 or A ECL 457

Laboratory to accompany Biology/Animal Ecology 457. Focus on survey methods, identification, relationships, distribution, habits, and habitats of amphibians and reptiles.

BIOL 458. Ornithology.

(Cross-listed with A ECL). (2-3) Cr. 3. S. Prereq: A ECL 365 or BIOL 351

Biology, evolution, ecology and taxonomy of birds. Emphasis on structure, physiology, behavior, communication, navigation, reproduction, and conservation. Laboratory exercises complement lecture topics, emphasize identification and distribution of Midwest birds, and include field trips.

BIOL 458L. Ornithology Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. S. Prereq: BIOL 351 or AECL/BIOL 365. Concurrent enrollment in AECL/BIOL 458 is required.

Laboratory complements lecture topics with emphasis on external anatomy, identification and distribution of Midwest birds, and field trips.

BIOL 459. Mammalogy.

(Dual-listed with EEOB 559). (Cross-listed with A ECL). (2-3) Cr. 3. S. Prereq: BIOL 351 or A ECL 365

Biology, ecology, and evolution of mammals. Emphasis on structure, physiological adaptation to different environments, behavior, reproduction, roles of mammals in ecosystems, and conservation. Laboratory focus on identification, distribution, habits, and habitats of mammals.

BIOL 459L. Mammalogy Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. S. Prereq: BIOL 351 or BIOL/AECL 365; concurrent enrollment in AECL 459 or BIOL 459 required.

Laboratory focus on identification, survey methods, distribution, habits, and habitats of mammals. Several field trips.

BIOL 462. Evolutionary Genetics.

(Cross-listed with GEN). (3-0) Cr. 3. S. Prereq: BIOL 315

The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change.

BIOL 465. Morphometric Analysis.

(Dual-listed with EEOB 565). (3-2) Cr. 4. Alt. S., offered even-numbered years. Prereq: STAT 401

A comprehensive overview of the theory and methods for the analysis of biological shape with emphasis on data acquisition, standardization, statistical analysis, and visualization of results. Methods for both landmark and outline data will be discussed.

BIOL 471. Introductory Conservation Biology.

Cr. 3. Prereq: BIOL 312

Examination of conservation issues from a population and community perspective. The role of genetics, demography, and environment in determining population viability, habitat fragmentation, reserve design, biodiversity assessment, and restoration ecology.

BIOL 472. Community Ecology.

(2-2) Cr. 3. S. Prereq: BIOL 312

The effect of interspecific interactions on the structure and dynamics of natural and managed communities; including concepts of guild structure and trophic web dynamics and their importance to the productivity, diversity, stability, and sustainability of communities. The implications of interspecifc interactions in the management of wild species will be emphasized with illustrative case histories of interactions between plants, invertebrates, and vertebrates.

BIOL 474. Plant Ecology.

(3-0) Cr. 3. S. Prereq: BIOL 312

Principles of plant population and community ecology.

BIOL 476. Functional Ecology.

(Dual-listed with EEOB 576). (3-0) Cr. 3. Alt. S., offered odd-numbered years. Prereq: BIOL 312

The nature of adaptations to physical and biotic environments. Biophysical, biomechanical, and physiological bases of the structure, form, growth, distribution, and abundance of organisms.

BIOL 480. Studies in Marine Biology.

Cr. 1-8. Repeatable.

Courses taken at Gulf Coast Research Laboratory and other marine biological stations are transferred to Iowa State University under this number.

BIOL 481. Summer Field Studies.

Cr. 1-8. Repeatable.

Courses taken at summer biological field stations are transferred to Iowa State University under this number. See www.biology.iastate.edu for links to field stations located in different biomes: coastal, Great Lakes, taiga, deciduous forests, deserts, Rocky Mountains.

BIOL 482. Tropical Biology.

Cr. 1-4. Repeatable, maximum of 8 credits. Prereq: One year of college biology; knowledge of Spanish desirable but not required

Students registering for courses taught by the Organization for Tropical Studies will receive credit for this ISU course when requesting a transfer of credits.

BIOL 484. Ecosystem Ecology.

(Cross-listed with ENSCI). (3-0) Cr. 3. Alt. S., offered odd-numbered years. Prereq: Combined 12 credits in biology, chemistry, and physics.

Introduction of the study of ecosystems and the biological and physical factors that influence their properties and dynamics. Conceptual foundations for ecosystem studies. Interactions among organisms, biological diversity, and ecosystem attributes. Quantitative analyses of accumulations, transformations, and fluxes of nutrients, water, and energy within and among ecosystems. Global change issues.

BIOL 486. Aquatic Ecology.

(Cross-listed with A ECL, ENSCI). (3-0) Cr. 3. F. Prereq: Biol 312 or EnSci 381 or EnSci 402 or NREM 301

Structure and function of aquatic ecosystems with application to fishery and pollution problems. Emphasis on lacustrine, riverine, and wetland ecology.

BIOL 486L. Aquatic Ecology Laboratory.

(Cross-listed with A ECL, ENSCI). (0-3) Cr. 1. F. Prereq: Concurrent enrollment in BIOL 486

Field trips and laboratory exercises to accompany 486. Hands-on experience with aquatic research and monitoring techniques and concepts.

BIOL 487. Microbial Ecology.

(Cross-listed with ENSCI, MICRO). (3-0) Cr. 3. F. Prereq: Six credits in biology and 6 credits in chemistry

Introduction to major functional groups of autotrophic and heterotrophic microorganisms and their roles in natural systems.

BIOL 488. Identification of Aquatic Organisms.

(0-3) Cr. 1. F.S.

On line taxonomic and identification exercises to accompany 486. Instruction and practice in the identification of algae, aquatic macrophytes, zooplankton, and benthos.

BIOL 489. Population Ecology.

(Dual-listed with EEOB 589). (2-2) Cr. 3. F. Prereq: BIOL 312, STAT 101 or STAT 104, a course in calculus, or graduate standing

Concepts and theories of population dynamics with emphasis on models of growth, predation, competition, and regulation.

BIOL 490. Independent Study.

Cr. 1-6. Repeatable, maximum of 9 credits. F.S.SS. Prereq: Permission of instructor.

Independent study opportunities for undergraduate students in the biological sciences. No more than 9 credits in Biol 490 may be counted toward graduation and of those, only 6 credits may be applied to the major.

BIOL 491. Undergraduate Teaching Experience.

Cr. 1-2. Repeatable. Prereq: Permission of supervising staff

For students registering to be undergraduate teaching assistants. Satisfactory-Fail grading only. Offered on a satisfactory-fail basis only.

BIOL 492. Preparing for Graduate School in the Biological Sciences.

(1-0) Cr. 1. F. Prereq: For life science majors; Minimum requirement: sophomore standing.

For students considering pursuing a graduate degree in the biological sciences. Professional development topics including the defining of academic and career areas of interest, finding and evaluating appropriate programs of graduate study, the graduate school application process, and developing a curriculum vita. Exploration of learning opportunities at field stations, research internships, and independent research activities.

BIOL 494. Biology Internship.

Cr. 1-3. Repeatable. Prereq: 8 credits in biology and permission of instructor

Intended to provide credit for significant professional experiences in biological sciences. A written proposal is required prior to registration. Intended for Biology majors.

BIOL 495. Undergraduate Seminar.

Cr. 1-3. Repeatable. F.S. Prereq: Permission of instructor

Content varies from year to year and may include detailed discussion of special topics in biology, current issues in biology, or careers in biology.

BIOL 498. Cooperative Education.

Cr. R. Repeatable. F.S.SS. Prereq: Permission of the Biology Program cooperative education coordinator

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

BIOL 499. Undergraduate Research Experience.

Cr. 1-6. Repeatable, maximum of 9 credits. F.S.SS. Prereq: Permission of instructor.

Research opportunities for undergraduate students in the biological sciences. No more than 9 credits in Biol 499 may be counted toward graduation and of those, only 6 credits may be applied to the major.

Genetics

GEN 110. Genetics Orientation.

(1-0) Cr. 1. F.

This course is intended for first year students and others new to the genetics major. Discussion of university policies and resources, requirements of the major, career opportunities, and other topics related to the first year experience.

GEN 298. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; sophomore classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 313. Principles of Genetics.

(Cross-listed with BIOL). (3-0) Cr. 3. F.S.SS. Prereq: BIOL 211, BIOL 211L, BIOL 212, and BIOL 212L

Introduction to the principles of transmission and molecular genetics of plants, animals, and bacteria. Recombination, structure and replication of DNA, gene expression, cloning, quantitative and population genetics. Students may receive graduation credit for no more than one of the following: Gen 260, Gen 313 and 313L, Gen 320, Biol 313 and 313L, and Agron 320.

GEN 313L. Genetics Laboratory.

(Cross-listed with BIOL). (0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 313

Laboratory to accompany 313. Students may receive graduation credit for no more than one of the following: Biol 313 and 313L, Gen 260, Gen 313, Gen 320, and Agron 320.

GEN 320. Genetics, Agriculture and Biotechnology.

(Cross-listed with AGRON). (3-0) Cr. 3. F.S. Prereq: BIOL 212

Lee and Salas Transmission genetics with an emphasis on applications in agriculture, the structure and expression of the gene, how genes behave in populations and how recombinant DNA technology can be used to improve agriculture. Credit for graduation will not be allowed for more than one of the following: Gen 260, 313, 320 and Biol 313 and 313L.

GEN 340. Human Genetics.

(3-0) Cr. 3. F.S.SS. Prereq: BIOL 313 or GEN 313

Fundamental concepts and current issues of human genetics. Human chromosome analysis, pedigree analysis, gene mapping, the human genome project, sex determination, genetics of the immune system, genetics of cancer, gene therapy, the genetic basis of human diversity, eugenics.

GEN 398. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; junior classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 409. Molecular Genetics.

(3-0) Cr. 3. F. Prereq: BIOL 313

The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes.

GEN 410. Analytical Genetics.

(3-0) Cr. 3. S. Prereq: GEN 409

The principles and practice of genetic analysis. Mendelian genetic analysis, mutational analysis of gene function, linkage and gene mapping, chromosomal aberrations, aneuploidy and polyploidy, extrachromosomal inheritance, analysis of genetic pathways.

GEN 444. Introduction to Bioinformatics.

(Cross-listed with BCB, BCBIO, BIOL, COM S, CPR E). (4-0) Cr. 4. F. Prereq: MATH 165 or STAT 401 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative and functional genomics, systems biology.

GEN 462. Evolutionary Genetics.

(Cross-listed with BIOL). (3-0) Cr. 3. F. Prereq: BIOL 315

The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change.

GEN 490. Independent Study.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: GEN 313, junior or senior classification, permission of instructor

Independent study in any area of genetics. Students may use no more than 9 credits of university-wide 490 or 499 credits (including Gen 490) toward the total of 120 credits required for graduation.

GEN 490S. Independent Study: Attendance and Critique of Genetics Seminars.

Cr. 1. Repeatable, maximum of 9 credits. F.S.SS. Prereq: GEN 313, junior or senior classification, permission of instructor

Attendance and critique of departmental seminars in BBMB, GDCB, or EEOB. Offered on a satisfactory-fail basis only. Students may use no more than 9 credits of university-wide 490 or 499 credits (including Gen 490S) toward the total of 120 credits required for graduation.

GEN 490U. Independent Study: Laboratory teaching experience.

Cr. 1-2. Repeatable, maximum of 9 credits. F.S.SS. Prereq: GEN 313, junior or senior classification, permission of instructor

For students registering to be undergraduate laboratory assistants. Offered on a satisfactory-fail basis only. Students may use no more than 9 credits of university wide 490 or 499 credits (including Gen 490U) toward the total of 120 credits required for graduation.

GEN 491. Undergraduate Seminar.

(1-0) Cr. 1. F.S. Prereq: Gen 409

Communication within the discipline based on comprehension, discussion, presentation, and critical evaluation of original research literature; survey of career paths within the genetics disciplines and approaches to obtaining positions; exposure to research publication and grantsmanship processes; ethical issues in genetics research; outcomes assessment activities.

GEN 498. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; senior classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 499. Genetics research.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: GEN 313, junior or senior classification, permission of instructor

Independent research in any area of genetics. Students may use no more than 9 credits of university-wide 490 or 499 credits (including Gen 490R) toward the total of 120 credits required for graduation.

GEN 499H. Genetics research for Honors.

Cr. 1-5. Repeatable. F.S.SS. Prereq: GEN 313, junior or senior classification, permission of instructor

Independent research in any area of genetics; for Honors students only. Students may use no more than 9 credits of university-wide 490 or 499 credits (including Gen 490H) toward the total of 120 credits required for graduation.

Courses primarily for graduate students, open to qualified undergraduate students

GDCB 505. Entrepreneurship in Science and Technology.

(3-0) Cr. 3. Alt. F., offered even-numbered years.

High level success at modern science requires entrepreneurship both in and outside the laboratory. Scientists are in a unique position to not only think, but to thrive, “outside of the box” and take unorthodox approaches to research that lead to positive paradigm shifts in our lives. Exploration of many facets of science, technology, industry and commerce, with frequent guest lectures from entrepreneurs.

GDCB 508. Biotechnology in Agriculture, Food, and Human Health.

(3-0) Cr. 3. Prereq: BIOL 211 and BIOL 212

Scientific principles and techniques in biotechnology. Products and applications in agriculture, food, and human health. Ethical, legal, and social implications of biotechnology. A research paper is required for graduate credit.

GDCB 510. Transmission Genetics.

(3-0) Cr. 3. F. Prereq: GEN 410 or graduate standing

In-depth investigations of modern research practices of transmission genetics. Designed for students interested in genetic research. Topics include: Mendelian genetic analysis, analysis of genetic pathways, mutational analysis of gene function, chromosomal mechanics, genetic mapping, epigenetic inheritance, human genetic analysis.

GDCB 511. Molecular Genetics.

(Cross-listed with MCDB). (3-0) Cr. 3. S. Prereq: BIOL 313 and BBMB 405

The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes.

GDCB 513. Plant Metabolism.

(Cross-listed with PLBIO). (2-0) Cr. 2. Alt. F., offered even-numbered years. Prereq: BIOL 330, PHYS 111, CHEM 331; one semester of biochemistry recommended

Photosynthesis, respiration, and other aspects of plant metabolism.

GDCB 520. Genetic Engineering.

(Cross-listed with BBMB, MCDB). (3-0) Cr. 3. Alt. S., offered even-numbered years. Prereq: GEN 411 or BBMB 405

Strategies and rationale of recombinant DNA technologies. The methodology of genetic engineering in basic research and implications for applied research will be considered. Topics include: basic tools of molecular cloning, targeted mutagenesis, fluorescent proteins, protein expression systems, and transgenic model systems.

GDCB 528. Advances in Molecular Cell Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: Courses in general cell biology and biochemistry

Cell biological processes including cell signaling, cell division, intracellular trafficking, biogenesis of organelles, cell adhesion and motility.

GDCB 533. Advances in Developmental Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: BIOL 314 or Biol 423

Fundamental principles in multicellular development. Emphasis on cellular and molecular regulation of developmental processes, and experimental approaches as illustrated in the current literature.

GDCB 536. Statistical Genetics.

(Cross-listed with STAT). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: STAT 401, STAT 447; GEN 320 or BIOL 313

Statistical models and methods for genetics covering models of population processes: selection, mutation, migration, population structure, and linkage disequilibrium, and inference techniques: genetic mapping, linkage analysis, and quantitative trait analysis. Applications include genetic map construction, gene mapping, genome-wide association studies (GWAS), inference about population structure, phylogenetic tree construction, and forensic and paternity identification.

GDCB 542. Introduction to Molecular Biology Techniques.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 542A. Introduction to Molecular Biology Techniques: DNA Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Includes genetic engineering procedures, sequencing, PCR, and genotyping. Offered on a satisfactory-fail basis only.

GDCB 542C. Introduction to Molecular Biology Techniques: Cell Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S. Prereq: Graduate classification

Includes immunophenotyping, ELISA, flow cytometry, microscopic techniques, image analysis, confocal, multiphoton and laser capture microdissection. Offered on a satisfactory-fail basis only.

GDCB 542D. Introduction to Molecular Biology Techniques: Plant Transformation.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification

Includes Agrobacterium and particle gun-mediated transformation of tobacco, Arabidopsis, and maize, and analysis of tranformants. Offered on a satisfactory-fail basis only.

GDCB 542E. Introducation to Molecular Biology Techniques: Proteomics..

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F. Prereq: Graduate classification

Includes two-dimensional electrophoresis, laser scanning, mass spectrometry, and database searching. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 542F. Introducation to Molecular Biology Tecniques: Metabolomics.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Metabolomics and the techniques involved in metabolite profiling. For non-chemistry majoring students who are seeking analytical aspects into their biological research projects. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 542G. Introduction to Molecular Biology Techniques: Genomic.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification

Offered on a satisfactory-fail basis only.

GDCB 544. Introduction to Bioinformatics.

(Cross-listed with BCB, COM S, CPR E). (4-0) Cr. 4. F. Prereq: MATH 165 or STAT 401 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative, functional genomics, and systems biology.

GDCB 545. Plant Molecular, Cell and Developmental Biology.

(Cross-listed with MCDB, PLBIO). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: Biol 313, BIOL 314, BIOL 330 or BBMB 405

Plant nuclear and organelle genomes; regulation of gene expression; hormone signaling; organization, function, and development of plant cells and subcellular structures; regulation of plant growth and development.

GDCB 556. Cellular, Molecular and Developmental Neuroscience.

(Cross-listed with B M S, NEURO). (3-0) Cr. 3. F. Prereq: BIOL 335 or BIOL 436; physics recommended

Fundamental principles of neuroscience including cellular and molecular neuroscience, nervous system development, sensory, motor and regulatory systems.

GDCB 557. Advanced Neuroscience Techniques.

(Cross-listed with NEURO). (2-0) Cr. 2. Alt. S., offered odd-numbered years. Prereq: Neuro 556 or equivalent course

Research methods and techniques; exercises and/or demonstrations representing individual faculty specialties.

GDCB 568. Bioinformatics II (Advanced Genome Informatics).

(Cross-listed with BCB, COM S, STAT). (3-0) Cr. 3. S. Prereq: BCB 567, BBMB 301, BIOL 315, STAT 430, credit or enrollment in GEN 411

Advanced sequence models. Basic methods in molecular phylogeny. Hidden Markov models. Genome annotation. DNA and protein motifs. Introduction to gene expression analysis.

GDCB 570. Bioinformatics IV (Computational Functional Genomics and Systems Biology).

(Cross-listed with BCB, COM S, CPR E, STAT). (3-0) Cr. 3. S. Prereq: BCB 567, BIOL 315, COM S 311 and either 208 or 228, GEN 411, STAT 430

Algorithmic and statistical approaches in computational functional genomics and systems biology. Elements of experiment design. Analysis of high throughput gene expression, proteomics, and other datasets obtained using system-wide measurements. Topological analysis, module discovery, and comparative analysis of gene and protein networks. Modeling, analysis, simulation and inference of transcriptional regulatory modules and networks, protein-protein interaction networks, metabolic networks, cells and systems: Dynamic systems, Boolean, and probabilistic models. Multi-scale, multi-granularity models. Ontology-driven, network based, and probabilistic approaches to information integration.

GDCB 590. Special Topics.

Cr. arr. Repeatable. Prereq: Permission of instructor

GDCB 596. Genomic Data Processing.

(Cross-listed with BCB, COM S). (3-0) Cr. 3. F. Prereq: Some experience in computation

Study the practical aspects of genomic data processing with an emphasis on hands-on projects. Topics include base-calling, sequence cleaning and contaminant removal; fragment assembly procedures and EST clustering methods; genome closure strategies and practices; sequence homology search and function prediction; and annotation and submission of GenBank reports. Next-generation sequencing topics like model genome resequencing, short-read assembly and transcriptome abundance measurement will also be covered.