Links to: Schedule of Classes and Complete Iowa State University Catalog

Bioinformatics and Computational Biology

BCBIO 1100. BCBIO Orientation.

(1-0) Cr. 0.5. F.

First 8 weeks. Orientation to the area of bioinformatics and computational biology. For students considering a major in BCBIO. Specializations and career opportunities. Offered on a satisfactory-fail basis only.

BCBIO 2110. Introduction to Bioinformatics and Computational Biology.

(3-0) Cr. 3. S.

Perl programming, molecular biology, biological databases, sequence alignment, homology search, identification of sequence patterns, construction of phylogenetic trees, gene function prediction, gene structure prediction, genomic annotation and comparative genomics.

BCBIO 4010. Bioinformatics of Sequences.

(Cross-listed with BIOL 4010/ COMS 4010/ GEN 4010).

(3-0) Cr. 3. F. Prereq: BCBIO 3220; (COMS 1270 OR COMS 2270); (MATH 1600 or MATH 1650); (MATH 1660 or STAT 3010); (STAT 1010 or STAT 1040 or STAT 3300) or Permission of Instructor

Application of computer science and statistics to molecular biology with a significant problem-solving component, including hands-on programming using Python to solve a variety of biological problems. String algorithms, sequence alignments, homology search, pattern discovery, genotyping, genome assembly, genome annotation, comparative genomics, protein structure. Offered odd-numbered years. (Typically Offered: Fall)

BCBIO 4420. Bioinformatics and Computational Biology Techniques.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 4420A. Bioinformatics and Computational Biology Techniques: Sequence Database Searching.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 4420B. Bioinformatics and Computational Biology: Protein Structure Databases, Visualization, and Prediction.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 4420C. Bioinformatics and Computational Biology Techniques: Phylogenetic Analysis.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 4420D. Bioinformatics and Computational Biology Techniques: Microarray Analysis.

(0.2-0.5) Cr. 0.5. Repeatable, maximum of 2 credits. S.SS. Prereq: BIOL 314 recommended

Modular minicourses consisting of guided tutorials and hands-on computer software exercises focused on fundamental problems, approaches, and software applications in bioinformatics and computational biology. Offered on a satisfactory-fail basis only.

BCBIO 4900. Independent Study.

Cr. 1-5. Repeatable, maximum of 9 credits. F.S.SS. Prereq: BCBIO 211, junior or senior classification, permission of instructor

Students in the College of Liberal Arts and Sciences may use no more than 9 credits of BCBIO 490 and 491 toward graduation.

BCBIO 4910. Team Research Projects.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: BCBIO 211, junior or senior classification, permission of instructor

Research projects in bioinformatics and computational biology done by teams of students. Students in the College of Liberal Arts and Sciences may use no more than 9 credits of BCBIO 490 and 491 toward graduation.

Biology

BIOL 1010. Introductory Biology.

(3-0) Cr. 3. F.S.SS.

Life considered at cellular, organism, and population levels. Function and diversity of the living world. Presentation of basic biological principles as well as topics and issues of current human interest. Does not satisfy biology major requirements.

BIOL 1100. Biology Major Orientation.

Cr. 1. F.

Orientation to the scope of the biological sciences, and discussion of professional opportunities. Required of first year biology majors. Offered on a satisfactory-fail basis only.

BIOL 1110. Opportunities in Biology.

(1-0) Cr. 0.5. S.

Introduction to biological science disciplines and professional opportunities through faculty presentations which examine a variety of current research topics. Offered on a satisfactory-fail basis only.

BIOL 1120. Transfer Student Orientation.

Cr. R. F.S.

Orientation to opportunities in Biology. Review of degree requirements and other information needed by students that have not participated in the first year Biology orientation courses. Offered on a satisfactory-fail basis only.

BIOL 1550. Human Biology.

(3-0) Cr. 3. F.S.

A survey course of human biology, including principal structures and functions of the body systems and the diseases and disorders associated with them. Designed to meet general education requirements in natural science. Not recommended for those seeking a career in the allied health professions or for students majoring in life science. Does not satisfy biology major requirements.

BIOL 1730. Environmental Biology.

(Cross-listed with ENV S). (3-0) Cr. 3. F.S.

An introduction to the structure and function of natural systems at scales from the individual to the biosphere and the complex interactions between humans and their environment. Discussions of human population growth, biodiversity, sustainability, resource use, and pollution. Does not satisfy biology major requirements.

BIOL 2010. Introduction to Environmental Issues.

(Cross-listed with ENSCI, ENV S). (2-0) Cr. 2. F.S.

Discussion of current and emerging environmental issues such as human population growth, energy use, loss of biodiversity, water resources, and climate change.

BIOL 2040. Biodiversity.

(Cross-listed with ENV S). (4-0) Cr. 2. S. Prereq: One course in life sciences

Survey of the major groups of organisms and biological systems. Definition, measurements, and patterns of distribution of organisms. Sources of information about biodiversity. Does not satisfy biology major requirements. Half semester course.

BIOL 2110. Principles of Biology I.

(3-0) Cr. 3. F.S. Prereq: High school biology

Introduction to the nature of life, including the diversity of microbial, plant, and animal life; the nature of heredity; evolution; and principles of ecology. Intended for life science majors.

BIOL 2110L. Principles of Biology Laboratory I.

(0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 2110

Laboratory to accompany 2110.

BIOL 2120. Principles of Biology II.

(3-0) Cr. 3. F.S. Prereq: High School Biology; high school chemistry or credit or enrollment in CHEM 1630 or CHEM 1770

Introduction to the chemical, molecular, and cellular basis of life; form and function of microbial, plant, and animal life. Intended for life science majors.

BIOL 2120L. Principles of Biology Laboratory II.

(0-3) Cr. 1. F.S. Prereq: credit or enrollment in BIOL 212

Laboratory to accompany 212.

BIOL 2510. Biological Processes in the Environment.

(Cross-listed with ENSCI). (3-0) Cr. 3. S.

Plant and microbial processes in environmental systems including their interactions with human activities.

BIOL 2550. Fundamentals of Human Anatomy.

(3-0) Cr. 3. F. Prereq: High School Biology and Chemistry, or BIOL 1010

An introduction to human anatomy, beginning with cells and tissues, surveying all body systems, relating form to function. Systems covered include: integumentary, bones and joints, muscles, nervous, sensory, endocrine, circulatory, lymphatic, respiratory, digestive, urinary, and reproductive. Pre-Medical students should consider Biol 3510 for their anatomy background. Does not satisfy biology major requirements.

BIOL 2550L. Fundamentals of Human Anatomy Laboratory.

(0-3) Cr. 1. F. Prereq: Credit or enrollment in BIOL 2550

Investigation of human anatomy using models and dissections of preserved organs and model mammals. Pre-Medical students should consider 3510 for their anatomy background. Does not satisfy biology major requirements.

BIOL 2560. Fundamentals of Human Physiology.

(3-0) Cr. 3. S. Prereq: High School Biology and Chemistry, or BIOL 101, or BIOL 255 (recommended)

An introduction to human physiology, studying the function of all body systems. Systems covered include: integumentary, bones and joints, muscles, nervous, sensory, endocrine, circulatory, lymphatic and immune, respiratory, digestive, urinary, and reproductive. Pre-Medical students should consider 3350 for their physiology background. Does not satisfy biology major requirements.

BIOL 2560L. Fundamentals of Human Physiology Laboratory.

(0-3) Cr. 1. S. Prereq: Credit or enrollment in BIOL 2560

Student-conducted experiments investigating concepts of human physiology with computer data acquisition and analysis. Interpretation of experimental results and preparation of lab reports. Pre-Medical students should consider 3350 for their anatomy and physiology background. Does not satisfy biology major requirements.

BIOL 3070. Women in Science and Engineering.

(Cross-listed with W S). (3-0) Cr. 3. F. Prereq: a 2000 level course in science, engineering or women’s studies; ENGL 2500

The interrelationships of women and science and engineering examined from historical, sociological, philosophical, and biological perspectives. Factors contributing to under-representation; feminist critiques of science; examination of successful strategies. Does not satisfy biology major advanced credit requirements.

Meets U.S. Diversity Requirement

BIOL 3120. Ecology.

(Cross-listed with A ECL, ENSCI). (3-3) Cr. 4. F.SS. Prereq: BIOL 2110L and BIOL 2120L

Fundamental concepts and principles of ecology dealing with organisms, populations, communities and ecosystems. Laboratory and field exercises examine ecological principles and methods as well as illustrate habitats.

BIOL 3130. Principles of Genetics.

(Cross-listed with GEN). (3-0) Cr. 3. F.S.SS. Prereq: BIOL 2110, BIOL 2110L, BIOL 2120, and BIOL 2120L

Introduction to the principles of transmission and molecular genetics of plants, animals, and bacteria. Recombination, structure and replication of DNA, gene expression, cloning, quantitative and population genetics. Students may receive graduation credit for no more than one of the following: Gen 2600, Gen 3130 and 3130L, Gen 3200, Biol 3130 and 3130L, and Agron 3200.

BIOL 3130L. Genetics Laboratory.

(Cross-listed with GEN). (0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 3130

Laboratory to accompany 3130. Students may receive graduation credit for no more than one of the following: Biol 3130 and 3130L, Gen 2600, Gen 3130, Gen 3200, and Agron 3200.

BIOL 3140. Principles of Molecular Cell Biology.

(3-0) Cr. 3. F.S. Prereq: BIOL 2110, 2110L, 2120, 2120L.

Integration of elementary principles of metabolism, bioenergetics, cell structure and function to develop a molecular view of how the cell works.

BIOL 3150. Biological Evolution.

(3-0) Cr. 3. F.S. Prereq: BIOL 2110, BIOL 2110L, BIOL 2120, BIOL 2120L. Biol 3130 recommended.

The mechanisms of evolution. Topics in microevolution: population genetics, natural selection, genetic variation, and adaptation. Macroevolution: speciation, extinction, phylogeny, and major evolutionary patterns.

BIOL 3280. Molecular and Cellular Biology of Human Diseases.

Cr. 3. Prereq: BIOL 2120

Survey of molecular, genetic and cellular aspects of human diseases. Fundamental concepts of cell biology and how they are linked to the pathologies of different classes of human diseases. Recent scientific advances with an emphasis on new methods of diagnosis and treatment.

BIOL 3350. Principles of Human and Other Animal Physiology.

(3-3) Cr. 4. F.S. Prereq: BIOL 3140

Introduction to systemic functions with emphasis on mammals.

BIOL 3360. Ecological and Evolutionary Animal Physiology.

Cr. 3. Prereq: BIOL 2110, BIOL 2120

Study of mechanisms by which animals perform life-sustaining functions; the evolution and adaptive significance of physiology traits, the diversity of physiological mechanisms, and how physiology and ecology interact.

BIOL 3500. Comprehensive Human Anatomy.

(3-0) Cr. 3. F. Prereq: Credit in BIOL 2110 and BIOL 2120

Comprehensive survey of human anatomy, emphasizing structural and functional relationships of major organ systems. Compartmental study of normal anatomy; practical clinical application of anatomical regions.

BIOL 3510. Comparative Chordate Anatomy.

(3-4) Cr. 5. S. Prereq: BIOL 2120, junior classification

The evolution of chordates as reflected in the anatomy of extinct and living forms. Lecture topics include the history and diversity of chordates; comparisons of anatomic structures among major groups, the adaptive significance of anatomic structures. Laboratory involves dissection of representative species.

BIOL 3520. Vertebrate Histology.

(3-3) Cr. 4. S. Prereq: BIOL 2120

Microscopic structure of vertebrate tissues and organs, with an introduction to histological techniques.

BIOL 3530. Introductory Parasitology.

(Cross-listed with MICRO, V PTH). (3-3) Cr. 4. S. Prereq: BIOL 2120

Biology and host-parasite relationships of major groups of animal parasites, and techniques of diagnosing and studying parasites.

BIOL 3540. Animal Behavior.

(3-0) Cr. 3. F. Prereq: BIOL 2120

Ethological and sociobiological approaches to animal behavior. Genetic and developmental aspects of behavior, biological rhythms, orientation (including navigation, migration), communication, and social behavior (mating, aggression, parental care).

BIOL 3540L. Laboratory in Animal Behavior.

(0-3) Cr. 1. F. Prereq: Credit or enrollment in BIOL 3540

Laboratory techniques for observation, description and analysis of animal activities; independent projects.

BIOL 3550. Plants and People.

(3-0) Cr. 3. S. Prereq: Credit in BIOL 2110 and BIOL 2110L

Uses of plants and fungi by humans and the importance of plants in the past, present and future. Discussion of fruits, vegetables, grains, herbs, spices, beverages, oils, fibers, wood, medicines, and drugs, in the context of their agricultural, cultural, and economic roles in modern societies. Emphasis on origins and worldwide diversity of culturally important plants, their characteristics, and uses.

BIOL 3560. Dendrology.

(Cross-listed with FOR). (2-4) Cr. 4. F. Prereq: BIOL 2110

Identification and ecology of North American woody plant species. Importance of woody plants in timber production and wildlife habitat. Natural disturbances, human impacts, management and restoration concerns for major North American forest regions will be addressed.

BIOL 3640. Invertebrate Biology.

Cr. 3-4. F. Prereq: BIOL 2120

Emphasis on diversity, development, physiology and behavior of invertebrate organisms- the “spineless wonders” of the world. Laboratory involves hands-on study and investigation of living invertebrates.

BIOL 3650. Vertebrate Biology.

(Cross-listed with A ECL). (3-2) Cr. 4. F. Prereq: BIOL 2120, BIOL 2120L

Evolution, biology, and classification of fish, amphibians, reptiles, birds, and mammals. Emphasis on a comparative analysis of the structure and function of organ systems. Laboratory exercises concentrate on morphology and identification of orders of vertebrates.

BIOL 3660. Plant Systematics.

(2-4) Cr. 4. S. Prereq: BIOL 2110

Introduction to plant phylogenetic systematics, plant classification, survey of flowering plant families, identification and field study of local plants.

BIOL 3710. Ecological Methods.

(Cross-listed with A ECL). (2-3) Cr. 3. F. Prereq: A ECL 3120; STAT 1010 or STAT 1040

Quantitative techniques used in management of natural resources with emphasis on inventory and manipulation of habitat and animal populations.

BIOL 3930. North American Field Trips in Biology.

Cr. 1-4. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, usually during break periods, to North American locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule.

BIOL 3930A. North American Field Trips in Biology: Pre-trip Seminar.

(1-0) Cr. 1. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Discussion of relevant biological and cultural topics during semester preceding extended field trips to North American locations of interest to biologists.

BIOL 3930B. North American Field Trips in Biology: North American Field trip.

Cr. 1-3. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trip to North American location under supervision of faculty member, usually during break periods, to North American locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule. Report required.

BIOL 3940. International Field Trips in Biology.

Cr. 1-4. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, usually during break periods, to international locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule.

Meets International Perspectives Requirement.

BIOL 3940A. International Field Trips in Biology: Pre-trip Seminar.

(1-0) Cr. 1. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Discussion of relevant biological and cultural topics during semester preceding extended field trip to international locations of interest to biologists.

BIOL 3940B. International Field Trips in Biology: Field Trip to International Location.

Cr. 1-3. Repeatable. Prereq: Two courses in the biological sciences and by approval of application

Extended field trips, under supervision of faculty member, usually during break periods, to international locations of interest to biologists. Inquire in the Biology Program Office, 103 Bessey Hall, for trip schedule. Offered on a satisfactory-fail basis only.

BIOL 4020. Introduction to Pathology.

(Cross-listed with V PTH). (3-0) Cr. 3. S. Prereq: BIOL 2110 and BIOL 2120 with labs

Introductory exploration of pathology as a medical discipline. This includes study of disease mechanisms via an introduction to general pathology topics (cell degeneration, necrosis, disturbances of growth, disturbances of blood flow, inflammation, neoplasia) and organ system-specific response to injury.

BIOL 4140. Life History and Reproductive Strategies.

(Dual-listed with EEOB 5140). (3-0) Cr. 3. F. Prereq: BIOL 3150 or equivalent; course in population ecology suggested.

Evolution of ecological adaptations at the individual, population, community and landscape levels. Emphasis is on evolutionary mechanisms and adaptive strategies; units and mechanisms of evolution, life history strategies, species interactions and organization of communities, behavior, and patterns of distribution, speciation and macroevolution.

BIOL 4230. Developmental Biology.

(3-0) Cr. 3. S. Prereq: BIOL 3130

Principles of embryogenesis and animal development. Establishment of body axes, organ and limb development, and specification of cell fates. Emphasis on cell signaling and the control of gene expression within the context of a developing organism. Medically relevant subjects will be discussed, including stem cells, cancer biology, fertilization, and cloning.

BIOL 4230L. Developmental Biology Laboratory.

(0-3) Cr. 1. S. Prereq: Credit or enrollment in BIOL 4230

Experiments and explorations illustrating fundamental principles of multicellular development.

BIOL 4280. Cell Biology.

(3-0) Cr. 3. S. Prereq: BIOL 3140

Selected topics on biological organization and function at the cellular level. Emphasis on biomembranes.

BIOL 4340. Endocrinology.

(Dual-listed with EEOB 5340). (3-0) Cr. 3. S. Prereq: BIOL 2110, BIOL 2120

Chemical integration of vertebrate organisms. The structure, development, and evolution of the endocrine glands and the function and structure of their hormones.

BIOL 4360. Neurobiology.

(3-0) Cr. 3. F. Prereq: BIOL 2120

Basic principles of brain function and development. Signaling of nerve cells, synaptic transmission, structure/function of ion channels and receptors, memory and synaptic plasticity, movement and central control, sensation and sensory processing, construction of neural circuits, early brain development, complex brain functions in health and disease.

BIOL 4510. Plant Evolution and Phylogeny.

(Dual-listed with EEOB 5510). (3-3) Cr. 4. F. Prereq: BIOL 3150 or equivalent.

Survey of land plant evolution; phylogenetic comparison of anatomical, reproductive, and life history specializations. Relationships among bryophytes, lycophytes, pteridophytes, gymnosperms, and angiosperms emphasizing significant evolutionary changes documented by paleobotanical, morphological, and molecular studies.

BIOL 4540. Plant Anatomy.

(3-3) Cr. 4. F. Prereq: BIOL 2120L; BIOL 3660 recommended

Characteristics of cell and tissue types in vascular plants. Anatomy of developing and mature stems, roots, and leaves, including secondary (woody) growth. Introduction to the special anatomy of flowers and seeds.

BIOL 4550. Bryophyte and Lichen Biodiversity.

(Dual-listed with EEOB 5550). Cr. 3. Prereq: BIOL 2110, BIOL 2110L

Introduction to the biology and ecology of mosses, liverworts, and lichens. Emphasis on identification and diversity of local representatives of these three groups of organisms. Required field trips and service-learning.

BIOL 4560. Principles of Mycology.

(Cross-listed with MICRO). (2-3) Cr. 3. F. Prereq: 10 credits in biological sciences

Morphology, diversity and ecology of fungi; their relation to agriculture and industry and human health.

BIOL 4570. Herpetology.

(Cross-listed with A ECL). (2-0) Cr. 2. F. Prereq: BIOL 3510 or BIOL 3650

Biology, ecology, and evolution of amphibians (salamanders, frogs, caecilians) and reptiles (lizards, snakes, tuatara, turtles, crocodilians). Emphasis on structure, physiological adaptation to different environments, behavior, reproduction, roles of amphibians and reptiles in ecosystems, and conservation. Laboratory focus on survey methods, identification, relationships, distribution, habits, and habitats of amphibians and reptiles.

BIOL 4570L. Herpetology Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. F. Prereq: BIOL 3510 or BIOL/A ECL 3650; concurrent registration in BIOL 4570 or A ECL 4570

Laboratory to accompany Biology/Animal Ecology 4570. Focus on survey methods, identification, relationships, distribution, habits, and habitats of amphibians and reptiles.

BIOL 4580. Ornithology.

(Cross-listed with A ECL). (2-3) Cr. 3. S. Prereq: A ECL 3650 or BIOL 3510

Biology, evolution, ecology and taxonomy of birds. Emphasis on structure, physiology, behavior, communication, navigation, reproduction, and conservation. Laboratory exercises complement lecture topics, emphasize identification and distribution of Midwest birds, and include field trips.

BIOL 4580L. Ornithology Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. S. Prereq: BIOL 3510 or AECL/BIOL 3650. Concurrent enrollment in AECL/BIOL 4580 is required.

Laboratory complements lecture topics with emphasis on external anatomy, identification and distribution of Midwest birds, and field trips.

BIOL 4590. Mammalogy.

(Dual-listed with EEOB 5590). (Cross-listed with A ECL). (2-3) Cr. 3. S. Prereq: BIOL 3510 or A ECL 3650

Biology, ecology, and evolution of mammals. Emphasis on structure, physiological adaptation to different environments, behavior, reproduction, roles of mammals in ecosystems, and conservation. Laboratory focus on identification, distribution, habits, and habitats of mammals.

BIOL 4590L. Mammalogy Laboratory.

(Cross-listed with A ECL). (0-3) Cr. 1. S. Prereq: BIOL 3510 or BIOL/AECL 3650; concurrent enrollment in AECL 4590 or BIOL 4590 required.

Laboratory focus on identification, survey methods, distribution, habits, and habitats of mammals. Several field trips.

BIOL 4620. Evolutionary Genetics.

(Cross-listed with GEN). (3-0) Cr. 3. S. Prereq: BIOL 3150

The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change.

BIOL 4650. Morphometric Analysis.

(Dual-listed with EEOB 5650). (3-2) Cr. 4. Alt. S., offered even-numbered years. Prereq: STAT 4010

A comprehensive overview of the theory and methods for the analysis of biological shape with emphasis on data acquisition, standardization, statistical analysis, and visualization of results. Methods for both landmark and outline data will be discussed.

BIOL 4710. Introductory Conservation Biology.

Cr. 3. Prereq: BIOL 3120

Examination of conservation issues from a population and community perspective. The role of genetics, demography, and environment in determining population viability, habitat fragmentation, reserve design, biodiversity assessment, and restoration ecology.

BIOL 4740. Plant Ecology.

(3-0) Cr. 3. S. Prereq: BIOL 3120

Principles of plant population and community ecology.

BIOL 4760. Functional Ecology.

(Dual-listed with EEOB 5760). (3-0) Cr. 3. Alt. S., offered odd-numbered years. Prereq: BIOL 3120

The nature of adaptations to physical and biotic environments. Biophysical, biomechanical, and physiological bases of the structure, form, growth, distribution, and abundance of organisms.

BIOL 4800. Studies in Marine Biology.

Cr. 1-8. Repeatable.

Courses taken at Gulf Coast Research Laboratory and other marine biological stations are transferred to Iowa State University under this number.

BIOL 4810. Summer Field Studies.

Cr. 1-8. Repeatable.

Courses taken at summer biological field stations are transferred to Iowa State University under this number. See www.biology.iastate.edu for links to field stations located in different biomes: coastal, Great Lakes, taiga, deciduous forests, deserts, Rocky Mountains.

BIOL 4820. Tropical Biology.

Cr. 1-4. Repeatable, maximum of 8 credits. Prereq: One year of college biology; knowledge of Spanish desirable but not required

Students registering for courses taught by the Organization for Tropical Studies will receive credit for this ISU course when requesting a transfer of credits.

BIOL 4840. Ecosystem Ecology.

(Cross-listed with ENSCI). (3-0) Cr. 3. Alt. S., offered odd-numbered years. Prereq: Combined 12 credits in biology, chemistry, and physics.

Introduction of the study of ecosystems and the biological and physical factors that influence their properties and dynamics. Conceptual foundations for ecosystem studies. Interactions among organisms, biological diversity, and ecosystem attributes. Quantitative analyses of accumulations, transformations, and fluxes of nutrients, water, and energy within and among ecosystems. Global change issues.

BIOL 4860. Aquatic Ecology.

(Cross-listed with A ECL, ENSCI). (3-0) Cr. 3. F. Prereq: Biol 3120 or EnSci 3810 or EnSci 4020 or NREM 3010

Structure and function of aquatic ecosystems with application to fishery and pollution problems. Emphasis on lacustrine, riverine, and wetland ecology.

BIOL 4860L. Aquatic Ecology Laboratory.

(Cross-listed with A ECL, ENSCI). (0-3) Cr. 1. F. Prereq: Concurrent enrollment in BIOL 4860

Field trips and laboratory exercises to accompany 4860. Hands-on experience with aquatic research and monitoring techniques and concepts.

BIOL 4870. Microbial Ecology.

(Cross-listed with ENSCI, MICRO). (3-0) Cr. 3. F. Prereq: Six credits in biology and 6 credits in chemistry

Introduction to major functional groups of autotrophic and heterotrophic microorganisms and their roles in natural systems.

BIOL 4880. Identification of Aquatic Organisms.

(0-3) Cr. 1. F.S.

On line taxonomic and identification exercises to accompany 4860. Instruction and practice in the identification of algae, aquatic macrophytes, zooplankton, and benthos.

BIOL 4890. Population Ecology.

(Dual-listed with EEOB 5890). (2-2) Cr. 3. F. Prereq: BIOL 3120, STAT 1010 or STAT 1040, a course in calculus, or graduate standing

Concepts and theories of population dynamics with emphasis on models of growth, predation, competition, and regulation.

BIOL 4900. Independent Study.

Cr. 1-6. Repeatable, maximum of 9 credits. F.S.SS. Prereq: Permission of instructor.

Independent study opportunities for undergraduate students in the biological sciences. No more than 9 credits in Biol 490 may be counted toward graduation and of those, only 6 credits may be applied to the major.

BIOL 4910. Undergraduate Teaching Experience.

Cr. 1-2. Repeatable. Prereq: Permission of supervising staff

For students registering to be undergraduate teaching assistants. Satisfactory-Fail grading only. Offered on a satisfactory-fail basis only.

BIOL 4920. Preparing for Graduate School in the Biological Sciences.

(1-0) Cr. 1. F. Prereq: For life science majors; Minimum requirement: sophomore standing.

For students considering pursuing a graduate degree in the biological sciences. Professional development topics including the defining of academic and career areas of interest, finding and evaluating appropriate programs of graduate study, the graduate school application process, and developing a curriculum vita. Exploration of learning opportunities at field stations, research internships, and independent research activities.

BIOL 4940. Biology Internship.

Cr. 1-3. Repeatable. Prereq: 8 credits in biology and permission of instructor

Intended to provide credit for significant professional experiences in biological sciences. A written proposal is required prior to registration. Intended for Biology majors.

BIOL 4950. Undergraduate Seminar.

Cr. 1-3. Repeatable. F.S. Prereq: Permission of instructor

Content varies from year to year and may include detailed discussion of special topics in biology, current issues in biology, or careers in biology.

BIOL 4980. Cooperative Education.

Cr. R. Repeatable. F.S.SS. Prereq: Permission of the Biology Program cooperative education coordinator

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

BIOL 4990. Undergraduate Research Experience.

Cr. 1-6. Repeatable, maximum of 9 credits. F.S.SS. Prereq: Permission of instructor.

Research opportunities for undergraduate students in the biological sciences. No more than 9 credits in Biol 499 may be counted toward graduation and of those, only 6 credits may be applied to the major.

Genetics

GEN 1100. Genetics Orientation.

(1-0) Cr. 1. F.

This course is intended for first year students and others new to the genetics major. Discussion of university policies and resources, requirements of the major, career opportunities, and other topics related to the first year experience.

GEN 2980. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; sophomore classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 3130. Principles of Genetics.

(Cross-listed with BIOL). (3-0) Cr. 3. F.S.SS. Prereq: BIOL 2110, BIOL 2110L, BIOL 2120, and BIOL 2120L

Introduction to the principles of transmission and molecular genetics of plants, animals, and bacteria. Recombination, structure and replication of DNA, gene expression, cloning, quantitative and population genetics. Students may receive graduation credit for no more than one of the following: Gen 2600, Gen 3130 and 3130L, Gen 3200, Biol 3130 and 3130L, and Agron 3200.

GEN 3130L. Genetics Laboratory.

(Cross-listed with BIOL). (0-3) Cr. 1. F.S. Prereq: Credit or enrollment in BIOL 3130

Laboratory to accompany 3130. Students may receive graduation credit for no more than one of the following: Biol 3130 and 3130L, Gen 2600, Gen 3130, Gen 3200, and Agron 3200.

GEN 3200. Genetics, Agriculture and Biotechnology.

(Cross-listed with AGRON). (3-0) Cr. 3. F.S. Prereq: BIOL 2120

Lee and Salas Transmission genetics with an emphasis on applications in agriculture, the structure and expression of the gene, how genes behave in populations and how recombinant DNA technology can be used to improve agriculture. Credit for graduation will not be allowed for more than one of the following: Gen 260, 313, 320 and Biol 313 and 313L.

GEN 3400. Human Genetics.

(3-0) Cr. 3. F.S.SS. Prereq: BIOL 3130 or GEN 3130

Fundamental concepts and current issues of human genetics. Human chromosome analysis, pedigree analysis, gene mapping, the human genome project, sex determination, genetics of the immune system, genetics of cancer, gene therapy, the genetic basis of human diversity, eugenics.

GEN 3980. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; junior classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 4090. Molecular Genetics.

(3-0) Cr. 3. F. Prereq: BIOL 3130

The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes.

GEN 4100. Analytical Genetics.

(3-0) Cr. 3. S. Prereq: GEN 4090

The principles and practice of genetic analysis. Mendelian genetic analysis, mutational analysis of gene function, linkage and gene mapping, chromosomal aberrations, aneuploidy and polyploidy, extrachromosomal inheritance, analysis of genetic pathways.

GEN 4440. Introduction to Bioinformatics.

(Cross-listed with BCB, BCBIO, BIOL, COM S, CPR E). (4-0) Cr. 4. F. Prereq: MATH 1650 or STAT 4010 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative and functional genomics, systems biology.

GEN 4620. Evolutionary Genetics.

(Cross-listed with BIOL). (3-0) Cr. 3. F. Prereq: BIOL 3150

The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change.

GEN 4900. Independent Study.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: GEN 3130, junior or senior classification, permission of instructor

Independent study in any area of genetics. Students may use no more than 9 credits of university-wide 4900 or 4990 credits (including Gen 4900) toward the total of 120 credits required for graduation.

GEN 4900S. Independent Study: Attendance and Critique of Genetics Seminars.

Cr. 1. Repeatable, maximum of 9 credits. F.S.SS. Prereq: GEN 3130, junior or senior classification, permission of instructor

Attendance and critique of departmental seminars in BBMB, GDCB, or EEOB. Offered on a satisfactory-fail basis only. Students may use no more than 9 credits of university-wide 4900 or 4990 credits (including Gen 4900S) toward the total of 120 credits required for graduation.

GEN 4900U. Independent Study: Laboratory teaching experience.

Cr. 1-2. Repeatable, maximum of 9 credits. F.S.SS. Prereq: GEN 3130, junior or senior classification, permission of instructor

For students registering to be undergraduate laboratory assistants. Offered on a satisfactory-fail basis only. Students may use no more than 9 credits of university wide 4900 or 4990 credits (including Gen 4900U) toward the total of 120 credits required for graduation.

GEN 4910. Undergraduate Seminar.

(1-0) Cr. 1. F.S. Prereq: Gen 4090

Communication within the discipline based on comprehension, discussion, presentation, and critical evaluation of original research literature; survey of career paths within the genetics disciplines and approaches to obtaining positions; exposure to research publication and grantsmanship processes; ethical issues in genetics research; outcomes assessment activities.

GEN 4980. Cooperative Education.

Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; senior classification

Required of all cooperative education students. Students must register for this course prior to commencing each work period.

GEN 4990. Genetics research.

Cr. 1-5. Repeatable, maximum of 9 credits. Prereq: GEN 3130, junior or senior classification, permission of instructor

Independent research in any area of genetics. Students may use no more than 9 credits of university-wide 4900 or 4990 credits (including Gen 4900R) toward the total of 120 credits required for graduation.

GEN 4990H. Genetics research for Honors.

Cr. 1-5. Repeatable. F.S.SS. Prereq: GEN 3130, junior or senior classification, permission of instructor

Independent research in any area of genetics; for Honors students only. Students may use no more than 9 credits of university-wide 4900 or 4990 credits (including Gen 4900H) toward the total of 120 credits required for graduation.

Courses primarily for graduate students, open to qualified undergraduate students

GDCB 5100. Transmission Genetics.

(3-0) Cr. 3. F. Prereq: GEN 4100 or graduate standing

In-depth investigations of modern research practices of transmission genetics. Designed for students interested in genetic research. Topics include: Mendelian genetic analysis, analysis of genetic pathways, mutational analysis of gene function, chromosomal mechanics, genetic mapping, epigenetic inheritance, human genetic analysis.

GDCB 5110. Advanced Molecular Genetics.

(Cross-listed with MCDB). (3-0) Cr. 3. S. Prereq: BIOL 3130 and BBMB 4050

The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes.

GDCB 5130. Plant Metabolism.

(Cross-listed with PLBIO). (2-0) Cr. 2. Alt. F., offered even-numbered years. Prereq: BIOL 3300, PHYS 111, CHEM 3310; one semester of biochemistry recommended

Photosynthesis, respiration, and other aspects of plant metabolism.

GDCB 5280. Advances in Molecular Cell Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: Courses in general cell biology and biochemistry

Cell biological processes including cell signaling, cell division, intracellular trafficking, biogenesis of organelles, cell adhesion and motility.

GDCB 5330. Advances in Developmental Biology.

(Cross-listed with MCDB). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: BIOL 3140 or Biol 4230

Fundamental principles in multicellular development. Emphasis on cellular and molecular regulation of developmental processes, and experimental approaches as illustrated in the current literature.

GDCB 5360. Statistical Genetics.

(Cross-listed with STAT). (3-0) Cr. 3. Alt. F., offered even-numbered years. Prereq: STAT 4010, STAT 4470; GEN 3200 or BIOL 3130

Statistical models and methods for genetics covering models of population processes: selection, mutation, migration, population structure, and linkage disequilibrium, and inference techniques: genetic mapping, linkage analysis, and quantitative trait analysis. Applications include genetic map construction, gene mapping, genome-wide association studies (GWAS), inference about population structure, phylogenetic tree construction, and forensic and paternity identification.

GDCB 5420. Introduction to Molecular Biology Techniques.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420A. Introduction to Molecular Biology Techniques: DNA Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Includes genetic engineering procedures, sequencing, PCR, and genotyping. Offered on a satisfactory-fail basis only.

GDCB 5420C. Introduction to Molecular Biology Techniques: Cell Techniques.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S. Prereq: Graduate classification

Includes immunophenotyping, ELISA, flow cytometry, microscopic techniques, image analysis, confocal, multiphoton and laser capture microdissection. Offered on a satisfactory-fail basis only.

GDCB 5420D. Introduction to Molecular Biology Techniques: Plant Transformation.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification

Includes Agrobacterium and particle gun-mediated transformation of tobacco, Arabidopsis, and maize, and analysis of tranformants. Offered on a satisfactory-fail basis only.

GDCB 5420E. Introducation to Molecular Biology Techniques: Proteomics..

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F. Prereq: Graduate classification

Includes two-dimensional electrophoresis, laser scanning, mass spectrometry, and database searching. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420F. Introducation to Molecular Biology Tecniques: Metabolomics.

(Cross-listed with B M S, BBMB, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification

Metabolomics and the techniques involved in metabolite profiling. For non-chemistry majoring students who are seeking analytical aspects into their biological research projects. Sessions in basic molecular biology techniques and related procedures. Offered on a satisfactory-fail basis only.

GDCB 5420G. Introduction to Molecular Biology Techniques: Genomic.

(Cross-listed with B M S, EEOB, FS HN, HORT, NREM, NUTRS, V MPM, VDPAM). Cr. 1. Repeatable. S. Prereq: Graduate classification

Offered on a satisfactory-fail basis only.

GDCB 5440. Introduction to Bioinformatics.

(Cross-listed with BCB, COM S, CPR E). (4-0) Cr. 4. F. Prereq: MATH 1650 or STAT 4010 or equivalent

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems. Topics include: database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative, functional genomics, and systems biology.

GDCB 5450. Plant Molecular, Cell and Developmental Biology.

(Cross-listed with MCDB, PLBIO). (3-0) Cr. 3. Alt. F., offered odd-numbered years. Prereq: Biol 3130, BIOL 3140, BIOL 3300 or BBMB 4050

Plant nuclear and organelle genomes; regulation of gene expression; hormone signaling; organization, function, and development of plant cells and subcellular structures; regulation of plant growth and development.

GDCB 5560. Cellular, Molecular and Developmental Neuroscience.

(Cross-listed with B M S, NEURO). (3-0) Cr. 3. F. Prereq: BIOL 3350 or BIOL 4360; physics recommended

Fundamental principles of neuroscience including cellular and molecular neuroscience, nervous system development, sensory, motor and regulatory systems.

GDCB 5570. Rotations in Neuroscience.

(Cross-listed with NEURO). (2-0) Cr. 2. Alt. S., offered odd-numbered years. Prereq: Neuro 5560 or equivalent course

Research methods and techniques; exercises and/or demonstrations representing individual faculty specialties.

GDCB 5680. Statistical Bioinformatics.

(Cross-listed with BCB, COM S, STAT). (3-0) Cr. 3. S. Prereq: BCB 5670, BBMB 3010, BIOL 3150, STAT 4300, credit or enrollment in GEN 4110

Advanced sequence models. Basic methods in molecular phylogeny. Hidden Markov models. Genome annotation. DNA and protein motifs. Introduction to gene expression analysis.

GDCB 5700. Systems Biology. 

(Cross-listed with BCB, COM S, CPR E, STAT). (3-0) Cr. 3. S. Prereq: BCB 5670, BIOL 3150, COM S 3110 and either 2080 or 2280, GEN 4110, STAT 4300

Algorithmic and statistical approaches in computational functional genomics and systems biology. Elements of experiment design. Analysis of high throughput gene expression, proteomics, and other datasets obtained using system-wide measurements. Topological analysis, module discovery, and comparative analysis of gene and protein networks. Modeling, analysis, simulation and inference of transcriptional regulatory modules and networks, protein-protein interaction networks, metabolic networks, cells and systems: Dynamic systems, Boolean, and probabilistic models. Multi-scale, multi-granularity models. Ontology-driven, network based, and probabilistic approaches to information integration.

GDCB 5900. Special Topics.

Cr. arr. Repeatable. Prereq: Permission of instructor