Eric Henderson

People
Professor
Eric Henderson photo

Eric teaches, promotes and practices rule breaking (when appropriate), fearlessness, and entrepreneurship in all facets of life. He has been involved in several companies including:

  • Bio Force Nanosciences, Inc., (biotech)
  • Aspera Corp (biotech)
  • Creodyne, llc (tech development)
  • Bumblefunk Music (media)
  • Hello Holdings (Griffle, GriffleGames, Griffle TV; media)
  • eMoJoCo, llc (art and media)

Eric is always looking for challenges and opportunities to work with young entrepreneurs. On the side Eric is a performing musician, fiction writer, tinkerer, and gadget freak.

Research

Our laboratory takes an enormously multidisciplinary approach to the study of the interface between biology and nanotechnology (or, more generally, life and technology). This area of inquiry can be labeled either bionanotechnology or synthetic biology. The label is of no importance. What is important is that 3.6 billion years of biological evolution has resulted a vast library of deeply tested pathways to addressing the dreams of nanotechnology. Our challenge is to understand and, in a practical fashion, transfer these insights to the emerging field of bionanotechnology.

Our research team has developed a complex, multidimensional mechanical system made out of DNA for testing molecular bonds and detecting molecular species. We have also developed enhancements to the process of DNA origami that expand the opportunity space for DNA-based nanosystems substantially. Additional ongoing projects involve “shape-shifting” DNA nanodevices and computational methods for generating the tools required to fully exploit the potential of DNA-based nanosystems.

The lab is currently funded by two multi-lab grants from the NSF designed to bridge the chasm between theory (Computer Science) and practice (Molecular Biology). Watch out!

Publications

  • Mathur, D. and Henderson, E. 2013. Complex DNA Nanostructures from Oligonucleotide Ensembles, ACS Synthetic Biology, 2(4), 180-185.
  • Radke, K. M., Nettikadan, Johnson, J. C., Vengasandra, S. G. and Henderson, E.. 2004. ViriChip enhances RT-PCR in biological fluids and environmental samples. Analytical Biochemistry 330(2) 350-352.
  • Lynch, M., Mosher, C., Huff, J., Nettikadan, S., Johnson, J., and Henderson, E.. 2004. Functional protein nanoarrays for biomarker profiling. Proteomics 6 (4), 1695-1702.
  • Johnson, J. C., Nettikadan, S. R., Vengasandra, S. G. and Henderson, E.. 2004. Analysis of solid-phase immobilized antibodies by atomic force microscopy. J. Biochem. Biophys. Meth. 59 (2) 167-180.
  • Xu, J., Lynch, M., Huff, J., Mosher, C., Ding, G., and Henderson, E.. 2003. Microfabricated quill-type deposition tools for the creations of biological micro/nano arrays. Biomedical Microdevices (2) (In press).
  • Nettikadan, S. R., Johnson, J. C., Vengasandra, S. G., Muys, J. and Henderson, E.. 2003. ViriChip: A solid phase assay for detection and identification of viruses by AFM. Nanotechnology 15, 383-389.
  • Nettikadan, S. R., Johnson, J. C., Mosher, C., and Henderson, E.. 2003. Virus particle detection by solid phase immunocapture and atomic force microscopy. Biophys. Biochem. Res. Comm. 311(2) 540-545

 

Area of Expertise: 
Bionanotechnology
Education: 
B.A., Biology, UCLA
Ph.D., Molecular Biology, UCLA
Post-doc., Telomere Biology, UC Berkeley
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